Analysis and solution of false-positives when testing CVA16 sera using an antibody assay against the EV71 virus

•The VP3 is the cross-reacting antigen in the EV71 IgM-capture ELISA with CVA16 serum.•The VP1 detection method is as sensitive as the virus-antibody detection method.•The VP1 detection method can resolve the false-positive problem. Hand, foot and mouth disease (HFMD) in humans is caused mainly by E...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Virus research 2013-09, Vol.176 (1-2), p.33-36
Hauptverfasser:	Wang, Changbing, You, Aiping, Tian, Xingui, Zhao, Mingqi, Chen, Yi, Lin, Tao, Zheng, Jianbin, Xiao, Misi, Zhang, Yingying, Kuang, Lu, Zhou, Zhenwen, Zhu, Bing
Format:	Artikel
Sprache:	eng
Schlagworte:	antibodies Antibodies, Viral - blood antigens Antigens, Viral Child Child, Preschool Coxsackievirus cross reaction Cross Reactions Cross-reactivity CVA16 Diagnostic Tests, Routine - methods early diagnosis Enterovirus Enterovirus - immunology Enterovirus A Enterovirus A, Human - immunology enzyme-linked immunosorbent assay Enzyme-Linked Immunosorbent Assay - methods EV71 False Positive Reactions foot-and-mouth disease hand, foot and mouth disease Hand, Foot and Mouth Disease - diagnosis Hand, Foot and Mouth Disease - virology Humans immunoblotting immunoglobulin M Immunoglobulin M - blood methods patients peptides Sensitivity and Specificity virion Virology - methods viruses VP1 VP3
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!