Hepatic Proteomic Responses in Marine Medaka (Oryzias melastigma) Chronically Exposed to Antifouling Compound Butenolide [5-octylfuran-2(5H)-one] or 4,5-Dichloro-2‑N‑Octyl-4-Isothiazolin-3-One (DCOIT)

The pollution of antifoulant SeaNine 211, with 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT) as active ingredient, in coastal environment raises concerns on its adverse effects, including endocrine disruption and impairment of reproductive function in marine organisms. In the present study, we...

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Veröffentlicht in:	Environmental science & technology 2015-02, Vol.49 (3), p.1851-1859
Hauptverfasser:	Chen, Lianguo, Sun, Jin, Zhang, Huoming, Au, Doris W. T, Lam, Paul K. S, Zhang, Weipeng, Bajic, Vladimir B, Qiu, Jian-Wen, Qian, Pei-Yuan
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Butyrolactone - analogs & derivatives 4-Butyrolactone - toxicity Animal reproduction Animals Aquatic ecology Biomarkers - metabolism Cytochrome P-450 Enzyme System - metabolism Endocrine disruptors Endocrine Disruptors - toxicity Energy consumption Female Fish Freshwater Glucuronosyltransferase - metabolism Glutathione Transferase - metabolism Liver - drug effects Liver - metabolism Male Metabolites Oryzias - metabolism Oryzias latipes Oryzias melastigma Protein expression Proteomics Thiazoles - toxicity Vitellogenins - metabolism Water Pollutants, Chemical - toxicity Water pollution
Online-Zugang:	Volltext
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