Photothermal Therapeutic Response of Cancer Cells to Aptamer–Gold Nanoparticle-Hybridized Graphene Oxide under NIR Illumination

The objective of this study was to synthesize a nanocomposite, aptamer–gold nanoparticle-hybridized graphene oxide (Apt-AuNP–GO), to facilitate targeted treatment of tumor cells by near-infrared (NIR) light-activatable photothermal therapy. We also investigated whether Apt-AuNP–GO with NIR illuminat...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	ACS applied materials & interfaces 2015-03, Vol.7 (9), p.5097-5106
Hauptverfasser:	Yang, Lingyan, Tseng, Yu-Ting, Suo, Guangli, Chen, Liliang, Yu, Jiantao, Chiu, Wei-Jane, Huang, Chih-Ching, Lin, Chia-Hua
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Regulatory Proteins - metabolism Aptamers, Nucleotide - chemistry Breast Neoplasms - pathology Breast Neoplasms - therapy Cell Survival - drug effects Cell Survival - radiation effects Female Gold - chemistry Graphite - chemistry HSP70 Heat-Shock Proteins - antagonists & inhibitors HSP70 Heat-Shock Proteins - metabolism Human Umbilical Vein Endothelial Cells Humans Infrared Rays MCF-7 Cells Metal Nanoparticles - chemistry Microscopy, Fluorescence Mucin-1 - metabolism Nanocomposites - chemistry Nanocomposites - therapeutic use Oxides - chemistry Phototherapy Purine Nucleosides - chemistry Purine Nucleosides - pharmacology Purine Nucleosides - therapeutic use Rhodamines - chemistry Temperature
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!