Prior Caspofungin Exposure in Patients with Hematological Malignancies Is a Risk Factor for Subsequent Fungemia Due to Decreased Susceptibility in Candida spp.: a Case-Control Study in Paris, France

Infections due to caspofungin-resistant Candida isolates in patients exposed to caspofungin therapy are increasing. We report here a nested case-control study which aimed at identifying factors associated with bloodstream infections caused by Candida spp. having reduced susceptibility to caspofungin...

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Veröffentlicht in:	Antimicrobial Agents and Chemotherapy 2011-11, Vol.55 (11), p.5358-5361
Hauptverfasser:	Blanchard, Elodie, Lortholary, Olivier, Boukris-Sitbon, Karine, Desnos-Ollivier, Marie, Dromer, Françoise, Guillemot, Didier
Format:	Artikel
Sprache:	eng
Schlagworte:	adults Aged antibiotic resistance Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal Agents Antifungal Agents - therapeutic use Biological and medical sciences blood flow Candida Candida - drug effects Candida - pathogenicity Case-Control Studies Clinical Therapeutics confidence interval drug effects Drug Resistance, Fungal drug therapy Echinocandins Echinocandins - therapeutic use Female France Fungemia Fungemia - drug therapy Hematologic Neoplasms Hematologic Neoplasms - drug therapy Hematologic Neoplasms - microbiology Human mycoses Humans Infectious diseases Life Sciences Lipopeptides Male Medical sciences microbiology Microbiology and Parasitology Middle Aged multivariate analysis Mycology Mycoses Mycotic sepsis odds ratio pathogenicity patients Pharmacology. Drug treatments Risk Factors therapeutic use therapeutics
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