Characterization of succinic semialdehyde dehydrogenase from Aspergillus niger

The catabolism of fungal 4-aminobutyrate (GABA) occurs via succinic semialdehyde (SSA). Succinic semialdehyde dehydrogenase (SSADH) from the acidogenic fungus Aspergillus niger was purified from GABA grown mycelia to the highest specific activity of 277 nmol min(-1) mg(-1), using phenyl Sepharose an...

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Veröffentlicht in:	Indian journal of experimental biology 2015-02, Vol.53 (2), p.67-74
Hauptverfasser:	Kumar, Santosh, Kumar, Sunil, Punekar, Narayan S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Monophosphate - metabolism Adenosine Monophosphate - pharmacology Aspergillus niger - enzymology Aspergillus niger - metabolism Benzaldehydes - metabolism Benzaldehydes - pharmacology Binding, Competitive Biocatalysis - drug effects Fungal Proteins - isolation & purification Fungal Proteins - metabolism gamma-Aminobutyric Acid - analogs & derivatives gamma-Aminobutyric Acid - metabolism gamma-Aminobutyric Acid - pharmacology Kinetics Mycelium - enzymology Mycelium - metabolism NAD - metabolism NAD - pharmacology Protein Binding Substrate Specificity Succinate-Semialdehyde Dehydrogenase - isolation & purification Succinate-Semialdehyde Dehydrogenase - metabolism
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