Modeling and Integral X-Ray, Optical, and MRI Visualization of Multiorgan Metastases of Orthotopic 4T1 Breast Carcinoma in BALB/c Mice

A model of highly metastasizing orthotopic allogeneic breast carcinoma was reproduced and standardized in experiments on BALB/c mice. 4T1 cells characterized by high metastatic activity were transfected with red fluorescent protein (RFP) gene or firefly luciferase (Luc2) gene. Unmodified 4T1 cells a...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2015-02, Vol.158 (4), p.581-588
Hauptverfasser:	Baklaushev, V. P., Grinenko, N. F., Yusubalieva, G. M., Abakumov, M. A., Gubskii, I. L., Cherepanov, S. A., Kashparov, I. A., Burenkov, M. S., Rabinovich, E. Z., Ivanova, N. V., Antonova, O. M., Chekhonin, V. P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Biomedicine Breast cancer Breast Neoplasms - pathology Cancer Carcinoma Cell Biology Contrast media Disease Models, Animal Female Fluorescence Internal Medicine Laboratory Medicine Liver cancer Luciferase Luciferases - pharmacology Luminescent Proteins - metabolism Luminescent Proteins - pharmacology Magnetic resonance imaging Magnetic Resonance Imaging - methods Metastasis Mice Mice, Inbred BALB C Models, Biological Neoplasm Metastasis - diagnostic imaging Neoplasm Metastasis - physiopathology Neoplasm Metastasis - ultrastructure Pathology Red Fluorescent Protein Survival Analysis Tomography, Optical X-Ray Microtomography
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