Dipeptidyl peptidase I is enriched in granules of in vitro- and in vivo- activated cytotoxic T lymphocytes

Recent studies have suggested that dipeptidyl peptidase I (DPPI) is the major post-translational processing enzyme responsible for generating activated myeloid and lymphoid granule serine proteases. The current studies assessed the relative levels of DPPI and granzyme A (BLT esterase) in B6 anti-H-2...

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Veröffentlicht in:	The Journal of immunology (1950) 1993-06, Vol.150 (11), p.4733-4742
Hauptverfasser:	Brown, GR, McGuire, MJ, Thiele, DL
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Ascitic Fluid - immunology Biological and medical sciences Cathepsin C Cytoplasmic Granules - enzymology Cytotoxicity, Immunologic - drug effects Dipeptides - pharmacology Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - metabolism Female Fundamental and applied biological sciences. Psychology Fundamental immunology Granzymes Immunobiology Immunosuppressive Agents - pharmacology Lymphocyte Activation Lymphoid cells: ontogeny, maturation, markers, receptors, circulation and recirculation Mice Mice, Inbred C57BL Mice, Inbred DBA Serine Endopeptidases - metabolism T-Lymphocytes, Cytotoxic - drug effects T-Lymphocytes, Cytotoxic - enzymology T-Lymphocytes, Cytotoxic - immunology
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