Susceptibility to Hemolytic-Uremic Syndrome Relates to Erythrocyte Glycosphingolipid Patterns

Hemolytic-uremic syndrome (HUS) is usually preceded by enteric infection by Shiga-like toxin-producing Escherichia coli (SLT-EC), but most children with SLT-EC diarrhea do not develop HUS. SLT toxicity depends on entry into the target cell via its host cell glycolipid receptor, globotriaosylceramide...

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Veröffentlicht in:	The Journal of infectious diseases 1993-08, Vol.168 (2), p.476-479
Hauptverfasser:	Newburg, David S., Chaturvedi, Prasoon, Lopez, Eduardo L., Devoto, Susana, Fayad, Alicia, Cleary, Thomas G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Bacterial diseases Bacterial diseases of the digestive system and abdomen Biological and medical sciences Blood groups Child Diarrhea Disease Susceptibility Erythrocytes Erythrocytes - metabolism Escherichia coli Glycolipids Glycosphingolipids Glycosphingolipids - metabolism Hemolytic uremic syndrome Hemolytic-Uremic Syndrome - blood Hemolytic-Uremic Syndrome - immunology Human bacterial diseases Humans Infectious diseases Lipids Medical sciences Receptors Toxins
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