Toxicity Studies of Partially Hydrolyzed Guar Gum

Toxicity Studies of Partially Hydrolyzed Guar Gum

The toxicity of partially hydrolyzed guar gum (PHGG, average molecular weight 20,000) was evaluated in a 28-day, repeated oral dosing study (gavage) in rats at doses of 0, 500, and 2,500 mg/kg/day and in Salmonella typhimurium, with and without metabolic activation. PHGG did not elicit any signs of...

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Veröffentlicht in:Journal of the American College of Toxicology 1994-08, Vol.13 (4), p.273-278
Hauptverfasser: Takahashi, Hidehisa, Yang, Sung Ik, Fujiki, Masaru, Kim, Mujo, Yamamoto, Takehiko, Greenberg, Norman A.
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Food toxicology
Medical sciences
Salmonella typhimurium
Toxicology
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Zusammenfassung:The toxicity of partially hydrolyzed guar gum (PHGG, average molecular weight 20,000) was evaluated in a 28-day, repeated oral dosing study (gavage) in rats at doses of 0, 500, and 2,500 mg/kg/day and in Salmonella typhimurium, with and without metabolic activation. PHGG did not elicit any signs of toxicity at the doses tested. PHGG was not mutagenic.
ISSN:0730-0913
DOI:10.3109/10915819409140599