A functional MRI study of motor dysfunction in Friedreich's ataxia

Abstract Friedreich's ataxia (FRDA) is the most common form of hereditary ataxia. In addition to proximal spinal cord and brain stem atrophy, mild to moderate atrophy of the cerebellum has been reported in advanced FRDA. The aim of this study was to examine dysfunction in motor-related areas in...

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Veröffentlicht in:	Brain research 2012-08, Vol.1471, p.138-154
Hauptverfasser:	Akhlaghi, H, Corben, L, Georgiou-Karistianis, N, Bradshaw, J, Delatycki, M.B, Storey, E, Egan, G.F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult atrophy Biological and medical sciences Brain - blood supply Brain - physiopathology Brain Mapping brain stem Cerebellum Cerebrospinal fluid. Meninges. Spinal cord cortex Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Female Finger tapping Fingers - innervation Friedreich Ataxia - complications Friedreich's ataxia Functional Laterality ganglia Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging Male Medical sciences Middle Aged Movement Disorders - etiology Movement Disorders - pathology Nervous system (semeiology, syndromes) Neurology Oxygen - blood Psychomotor Performance - physiology spinal cord Time Factors
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