Brain–blood barrier breakdown and pro-inflammatory mediators in neonate rats submitted meningitis by Streptococcus pneumoniae

Abstract Neonatal meningitis is an illness characterized by inflammation of the meninges and occurring within the birth and the first 28 days of life. Invasive infection by Streptococcus pneumoniae , meningitis and sepsis, in neonate is associated with prolonged rupture of membranes; maternal coloni...

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Veröffentlicht in:	Brain research 2012-08, Vol.1471, p.162-168
Hauptverfasser:	Barichello, Tatiana, Fagundes, Glauco D, Generoso, Jaqueline S, Paula Moreira, Ana, Costa, Caroline S, Zanatta, Jessiele R, Simões, Lutiana R, Petronilho, Fabricia, Dal-Pizzol, Felipe, Carvalho Vilela, Márcia, Lucio Teixeira, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Biological and medical sciences Blood-Brain Barrier - physiopathology Blood–brain barrier Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges Cerebral Cortex - metabolism Cerebral Cortex - microbiology Cerebral Cortex - pathology Chemokine chemokines cortex Cytokine Disease Models, Animal Fundamental and applied biological sciences. Psychology Gene Expression Regulation - physiology hippocampus Hippocampus - metabolism Hippocampus - microbiology Hippocampus - pathology inflammation Inflammation Mediators - metabolism interleukin-10 interleukin-6 meninges Meningitis Meningitis - etiology Meningitis - metabolism Meningitis - pathology mortality neonates Neurology Pneumococcal Infections - complications premature birth Rats Streptococcus pneumoniae Time Factors Vertebrates: nervous system and sense organs
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