Association of Transforming Growth Factor-Beta 1 Promoter Variant -509 C/T with Bronchial Asthma in South Indian Population

Transforming growth factor-beta 1 (TGF-β1) is a multifunctional cytokine that plays a pivotal role in airway remodeling observed in the asthmatic airways. C to T base substitution at -509 promoter position in the TGF-β1 gene leads to its increased expression which contributes to airway remodeling in...

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Veröffentlicht in:	Inflammation 2015-02, Vol.38 (1), p.409-414
Hauptverfasser:	Bandaru, Srinivas, Marri, Vijaya Kumar, Akka, Jyothy, Alvala, Mallika, Mundluru, Hema Prasad
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Asthma - diagnosis Asthma - epidemiology Asthma - genetics Biomedical and Life Sciences Biomedicine Female Genetic Association Studies - methods Genetic Variation - genetics Humans Immunology India - epidemiology Internal Medicine Male Middle Aged Pathology Pharmacology/Toxicology Population Surveillance Promoter Regions, Genetic - genetics Rheumatology Transforming Growth Factor beta1 - genetics
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