contest for precursors: channelling L-isoleucine synthesis in Corynebacterium glutamicum without byproduct formation

L-Isoleucine is an essential amino acid, which is required as a pharma product and feed additive. Its synthesis shares initial steps with that of L-lysine and L-threonine, and four enzymes of L-isoleucine synthesis have an enlarged substrate specificity involved also in L-valine and L-leucine synthe...

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