The role of serotonin and its receptors in activation of immune responses and inflammation

Serotonin or 5‐hydroxytryptamine (5‐HT) is a neurotransmitter and hormone that contributes to the regulation of various physiological functions by its actions in the central nervous system (CNS) and in the respective organ systems. Peripheral 5‐HT is predominantly produced by enterochromaffin (EC) c...

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Veröffentlicht in:	Acta Physiologica 2015-03, Vol.213 (3), p.561-574
Hauptverfasser:	Shajib, M. S., Khan, W. I.
Format:	Artikel
Sprache:	eng
Schlagworte:	5-HT 5-HT receptors Animals Anti-Inflammatory Agents - therapeutic use Bowel disease Central nervous system colitis Digestive system Enterochromaffin Cells - immunology Enterochromaffin Cells - metabolism Gastrointestinal tract Humans Immune response Inflammation Inflammation - immunology Inflammation - metabolism Inflammation - prevention & control Inflammation Mediators - immunology Inflammation Mediators - metabolism Inflammatory bowel diseases Neurons - immunology Neurons - metabolism Receptors, Serotonin - drug effects Receptors, Serotonin - immunology Receptors, Serotonin - metabolism Respiratory tract diseases Rheumatoid arthritis Serotonin Serotonin - immunology Serotonin - metabolism Serotonin Antagonists - therapeutic use Signal Transduction - drug effects
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