A second-generation Irish genome-wide association study for amyotrophic lateral sclerosis

Abstract Amyotrophic lateral sclerosis (ALS) is a heritable neurological disease for which the underlying genetic etiology is only partially understood. In Ireland, 83%–90% of cases are currently unexplained. Through large international collaborations, genome-wide association studies (GWASs) have su...

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Veröffentlicht in:	Neurobiology of aging 2015-02, Vol.36 (2), p.1221.e7-1221.e13
Hauptverfasser:	McLaughlin, Russell L, Kenna, Kevin P, Vajda, Alice, Bede, Peter, Elamin, Marwa, Cronin, Simon, Donaghy, Colette G, Bradley, Daniel G, Hardiman, Orla
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age of Onset Aged Alleles Amyotrophic lateral sclerosis Amyotrophic Lateral Sclerosis - epidemiology Amyotrophic Lateral Sclerosis - genetics Cohort Studies Female Genetic Predisposition to Disease - genetics Genome, Human - genetics Genome-wide association study Genome-Wide Association Study - methods Humans Imputation Internal Medicine Ireland - epidemiology Irish population Male Middle Aged Neurology Polymorphism, Single Nucleotide Risk
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