miR-137 restoration sensitizes multidrug-resistant MCF-7/ADM cells to anticancer agents by targeting YB-1

Multidrug resistance (MDR) to chemotherapeutic agents is a major obstacle to successful treatment in breast cancer patients. The aims of this study were to investigate whether miR-137 was involved in the regulation of MDR, and to explore the mechanism of miR-137 on the sensitivity of MCF-7/ADM cells...

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Veröffentlicht in:Acta biochimica et biophysica Sinica 2013-02, Vol.45 (2), p.80-86
Hauptverfasser: Zhu, Xiaolan, Li, Yuefeng, Shen, Huiling, Li, Hao, Long, Lulu, Hui, Lulu, Xu, Wenlin
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Sprache:eng
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