Voluntary Exercise Promotes Beneficial Anti-aging Mechanisms in SAMP8 Female Brain

Regular physical exercise mediates health and longevity promotion involving Sirtuin 1 (SIRT1)-regulated pathways. The anti-aging activity of SIRT1 is achieved, at least in part, by means of fine-tuning the adenosine monophosphate (AMP)-activated protein kinase (AMPK) pathway by preventing the transi...

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Veröffentlicht in:	Journal of molecular neuroscience 2015-02, Vol.55 (2), p.525-532
Hauptverfasser:	Bayod, Sergi, Guzmán-Brambila, Carolina, Sanchez-Roige, Sandra, Lalanza, Jaume F., Kaliman, Perla, Ortuño-Sahagun, Daniel, Escorihuela, Rosa M., Pallàs, Mercè
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Aging Aging - genetics Aging - metabolism Aging - physiology Alzheimer's disease AMP-Activated Protein Kinases - metabolism Animals Biomedical and Life Sciences Biomedicine Biosynthesis Brain - growth & development Brain - metabolism Brain - physiology Cell Biology Exercise Female Kinases Mice Neurochemistry Neurology Neurosciences Organ Specificity Oxidative Phosphorylation Physical Exertion Physical fitness Physiology Proteomics Senescence Sirtuin 1 - genetics Sirtuin 1 - metabolism
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