Systematic review of the incidence of herbal drug-induced liver injury in Korea
Herbal drugs have been generally believed to be safe, based on the natural sources and long clinical experience. With the increasing use of herbal medicine worldwide, the potential toxicity of herbal drugs, especially drug-induced liver injury (DILI), frequently becomes a medical issue. This study w...
Gespeichert in:
| Veröffentlicht in: | Journal of ethnopharmacology 2015-01, Vol.159, p.253-256 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 256 |
|---|---|
| container_issue | |
| container_start_page | 253 |
| container_title | Journal of ethnopharmacology |
| container_volume | 159 |
| creator | Oh, Soo-Jung Cho, Jung-Hyo Son, Chang-Gue |
| description | Herbal drugs have been generally believed to be safe, based on the natural sources and long clinical experience. With the increasing use of herbal medicine worldwide, the potential toxicity of herbal drugs, especially drug-induced liver injury (DILI), frequently becomes a medical issue. This study was aimed to estimate the incidence of DILI following herbal drug consumption in Korea
A literature search for herbal DILI in eight databases, including PubMed, Medline, the Cochrane Library, EMBASE, and four Korean electronic databases.
Six studies (three prospective and three retrospective) met the necessary criteria for assessment of the risk of DILI following herbal medicine exposure. The total number of participants in the six studies was 1699 (756 males and 943 females), and the incidence of herbal DILI varied from 0 to 1.92 among them. Total incidence of herbal DILI was 0.71% (12 patients with herbal DILI), and it was significantly higher in male (1.32%) than female (0.21%) respectively (p |
| doi_str_mv | 10.1016/j.jep.2014.11.027 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1660405791</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0378874114008113</els_id><sourcerecordid>1660405791</sourcerecordid><originalsourceid>FETCH-LOGICAL-c386t-2ab13a0e7276afd49f3b3c1f1b6bd2f6f701d425219d634d2868636ecdf0e2123</originalsourceid><addsrcrecordid>eNp9kMtOwzAQRS0EgvL4ADYoSzYJHjuxU7FCiJdA6gJYW449po7SpthJUf8eVwWWrK40OvdKcwg5B1oABXHVFi2uCkahLAAKyuQemUAtWS4ryffJhHJZ57Us4Ygcx9hSSiWU9JAcsaoUtKrlhMxeN3HAhR68yQKuPX5lvcuGOWZ-abzFpcHtYY6h0V1mw_iR-6UdDdqs82sMCWvHsEmRPfcB9Sk5cLqLePaTJ-T9_u7t9jF_mT083d685IbXYsiZboBripJJoZ0tp4433ICDRjSWOeEkBVuyisHUCl5aVotacIHGOooMGD8hl7vdVeg_R4yDWvhosOv0EvsxKhCClrSSU0go7FAT-hgDOrUKfqHDRgFVW4-qVcmj2npUACp5TJ2Ln_mxWaD9a_yKS8D1DsD0ZNIWVDR-a8v6gGZQtvf_zH8D22OCwg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1660405791</pqid></control><display><type>article</type><title>Systematic review of the incidence of herbal drug-induced liver injury in Korea</title><source>MEDLINE</source><source>ScienceDirect Journals (5 years ago - present)</source><creator>Oh, Soo-Jung ; Cho, Jung-Hyo ; Son, Chang-Gue</creator><creatorcontrib>Oh, Soo-Jung ; Cho, Jung-Hyo ; Son, Chang-Gue</creatorcontrib><description>Herbal drugs have been generally believed to be safe, based on the natural sources and long clinical experience. With the increasing use of herbal medicine worldwide, the potential toxicity of herbal drugs, especially drug-induced liver injury (DILI), frequently becomes a medical issue. This study was aimed to estimate the incidence of DILI following herbal drug consumption in Korea
A literature search for herbal DILI in eight databases, including PubMed, Medline, the Cochrane Library, EMBASE, and four Korean electronic databases.
Six studies (three prospective and three retrospective) met the necessary criteria for assessment of the risk of DILI following herbal medicine exposure. The total number of participants in the six studies was 1699 (756 males and 943 females), and the incidence of herbal DILI varied from 0 to 1.92 among them. Total incidence of herbal DILI was 0.71% (12 patients with herbal DILI), and it was significantly higher in male (1.32%) than female (0.21%) respectively (p<0.01). All of the patients that experienced DILI concomitantly ingested herbal medicine and conventional drugs.
This result showed the comprehensive data indicating the incident risk of hepatotoxicity in patients using herbal drugs in Korea, and presented the possibility of increased risk for the DILI by concurrent administration of herbal and conventional medicines.
[Display omitted]</description><identifier>ISSN: 0378-8741</identifier><identifier>EISSN: 1872-7573</identifier><identifier>DOI: 10.1016/j.jep.2014.11.027</identifier><identifier>PMID: 25460587</identifier><language>eng</language><publisher>Ireland: Elsevier Ireland Ltd</publisher><subject>Chemical and Drug Induced Liver Injury - epidemiology ; Chemical and Drug Induced Liver Injury - etiology ; Drug-induced liver injury (DILI) ; Female ; Herbal medicine ; Humans ; Incidence ; Male ; Plants, Medicinal - adverse effects ; Republic of Korea ; Safety</subject><ispartof>Journal of ethnopharmacology, 2015-01, Vol.159, p.253-256</ispartof><rights>2014 Elsevier Ireland Ltd</rights><rights>Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c386t-2ab13a0e7276afd49f3b3c1f1b6bd2f6f701d425219d634d2868636ecdf0e2123</citedby><cites>FETCH-LOGICAL-c386t-2ab13a0e7276afd49f3b3c1f1b6bd2f6f701d425219d634d2868636ecdf0e2123</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jep.2014.11.027$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25460587$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Oh, Soo-Jung</creatorcontrib><creatorcontrib>Cho, Jung-Hyo</creatorcontrib><creatorcontrib>Son, Chang-Gue</creatorcontrib><title>Systematic review of the incidence of herbal drug-induced liver injury in Korea</title><title>Journal of ethnopharmacology</title><addtitle>J Ethnopharmacol</addtitle><description>Herbal drugs have been generally believed to be safe, based on the natural sources and long clinical experience. With the increasing use of herbal medicine worldwide, the potential toxicity of herbal drugs, especially drug-induced liver injury (DILI), frequently becomes a medical issue. This study was aimed to estimate the incidence of DILI following herbal drug consumption in Korea
A literature search for herbal DILI in eight databases, including PubMed, Medline, the Cochrane Library, EMBASE, and four Korean electronic databases.
Six studies (three prospective and three retrospective) met the necessary criteria for assessment of the risk of DILI following herbal medicine exposure. The total number of participants in the six studies was 1699 (756 males and 943 females), and the incidence of herbal DILI varied from 0 to 1.92 among them. Total incidence of herbal DILI was 0.71% (12 patients with herbal DILI), and it was significantly higher in male (1.32%) than female (0.21%) respectively (p<0.01). All of the patients that experienced DILI concomitantly ingested herbal medicine and conventional drugs.
This result showed the comprehensive data indicating the incident risk of hepatotoxicity in patients using herbal drugs in Korea, and presented the possibility of increased risk for the DILI by concurrent administration of herbal and conventional medicines.
[Display omitted]</description><subject>Chemical and Drug Induced Liver Injury - epidemiology</subject><subject>Chemical and Drug Induced Liver Injury - etiology</subject><subject>Drug-induced liver injury (DILI)</subject><subject>Female</subject><subject>Herbal medicine</subject><subject>Humans</subject><subject>Incidence</subject><subject>Male</subject><subject>Plants, Medicinal - adverse effects</subject><subject>Republic of Korea</subject><subject>Safety</subject><issn>0378-8741</issn><issn>1872-7573</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtOwzAQRS0EgvL4ADYoSzYJHjuxU7FCiJdA6gJYW449po7SpthJUf8eVwWWrK40OvdKcwg5B1oABXHVFi2uCkahLAAKyuQemUAtWS4ryffJhHJZ57Us4Ygcx9hSSiWU9JAcsaoUtKrlhMxeN3HAhR68yQKuPX5lvcuGOWZ-abzFpcHtYY6h0V1mw_iR-6UdDdqs82sMCWvHsEmRPfcB9Sk5cLqLePaTJ-T9_u7t9jF_mT083d685IbXYsiZboBripJJoZ0tp4433ICDRjSWOeEkBVuyisHUCl5aVotacIHGOooMGD8hl7vdVeg_R4yDWvhosOv0EvsxKhCClrSSU0go7FAT-hgDOrUKfqHDRgFVW4-qVcmj2npUACp5TJ2Ln_mxWaD9a_yKS8D1DsD0ZNIWVDR-a8v6gGZQtvf_zH8D22OCwg</recordid><startdate>20150115</startdate><enddate>20150115</enddate><creator>Oh, Soo-Jung</creator><creator>Cho, Jung-Hyo</creator><creator>Son, Chang-Gue</creator><general>Elsevier Ireland Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T2</scope><scope>7U1</scope><scope>7U2</scope><scope>C1K</scope></search><sort><creationdate>20150115</creationdate><title>Systematic review of the incidence of herbal drug-induced liver injury in Korea</title><author>Oh, Soo-Jung ; Cho, Jung-Hyo ; Son, Chang-Gue</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c386t-2ab13a0e7276afd49f3b3c1f1b6bd2f6f701d425219d634d2868636ecdf0e2123</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Chemical and Drug Induced Liver Injury - epidemiology</topic><topic>Chemical and Drug Induced Liver Injury - etiology</topic><topic>Drug-induced liver injury (DILI)</topic><topic>Female</topic><topic>Herbal medicine</topic><topic>Humans</topic><topic>Incidence</topic><topic>Male</topic><topic>Plants, Medicinal - adverse effects</topic><topic>Republic of Korea</topic><topic>Safety</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Oh, Soo-Jung</creatorcontrib><creatorcontrib>Cho, Jung-Hyo</creatorcontrib><creatorcontrib>Son, Chang-Gue</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Risk Abstracts</collection><collection>Safety Science and Risk</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Journal of ethnopharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Oh, Soo-Jung</au><au>Cho, Jung-Hyo</au><au>Son, Chang-Gue</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Systematic review of the incidence of herbal drug-induced liver injury in Korea</atitle><jtitle>Journal of ethnopharmacology</jtitle><addtitle>J Ethnopharmacol</addtitle><date>2015-01-15</date><risdate>2015</risdate><volume>159</volume><spage>253</spage><epage>256</epage><pages>253-256</pages><issn>0378-8741</issn><eissn>1872-7573</eissn><abstract>Herbal drugs have been generally believed to be safe, based on the natural sources and long clinical experience. With the increasing use of herbal medicine worldwide, the potential toxicity of herbal drugs, especially drug-induced liver injury (DILI), frequently becomes a medical issue. This study was aimed to estimate the incidence of DILI following herbal drug consumption in Korea
A literature search for herbal DILI in eight databases, including PubMed, Medline, the Cochrane Library, EMBASE, and four Korean electronic databases.
Six studies (three prospective and three retrospective) met the necessary criteria for assessment of the risk of DILI following herbal medicine exposure. The total number of participants in the six studies was 1699 (756 males and 943 females), and the incidence of herbal DILI varied from 0 to 1.92 among them. Total incidence of herbal DILI was 0.71% (12 patients with herbal DILI), and it was significantly higher in male (1.32%) than female (0.21%) respectively (p<0.01). All of the patients that experienced DILI concomitantly ingested herbal medicine and conventional drugs.
This result showed the comprehensive data indicating the incident risk of hepatotoxicity in patients using herbal drugs in Korea, and presented the possibility of increased risk for the DILI by concurrent administration of herbal and conventional medicines.
[Display omitted]</abstract><cop>Ireland</cop><pub>Elsevier Ireland Ltd</pub><pmid>25460587</pmid><doi>10.1016/j.jep.2014.11.027</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0378-8741 |
| ispartof | Journal of ethnopharmacology, 2015-01, Vol.159, p.253-256 |
| issn | 0378-8741 1872-7573 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1660405791 |
| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Chemical and Drug Induced Liver Injury - epidemiology Chemical and Drug Induced Liver Injury - etiology Drug-induced liver injury (DILI) Female Herbal medicine Humans Incidence Male Plants, Medicinal - adverse effects Republic of Korea Safety |
| title | Systematic review of the incidence of herbal drug-induced liver injury in Korea |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T01%3A42%3A40IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Systematic%20review%20of%20the%20incidence%20of%20herbal%20drug-induced%20liver%20injury%20in%20Korea&rft.jtitle=Journal%20of%20ethnopharmacology&rft.au=Oh,%20Soo-Jung&rft.date=2015-01-15&rft.volume=159&rft.spage=253&rft.epage=256&rft.pages=253-256&rft.issn=0378-8741&rft.eissn=1872-7573&rft_id=info:doi/10.1016/j.jep.2014.11.027&rft_dat=%3Cproquest_cross%3E1660405791%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1660405791&rft_id=info:pmid/25460587&rft_els_id=S0378874114008113&rfr_iscdi=true |