A novel approach for the development and optimization of self emulsifying drug delivery system using HLB and response surface methodology: Application to fenofibrate encapsulation

[Display omitted] The aim of this work was to elaborate a novel approach for the development and optimization of self-emulsifying drug delivery system (SEDDS), using response surface methodology and hydrophilic lipophilic balance (HLB). Fenofibrate was selected as drug model. Rapid selection of exci...

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Veröffentlicht in:	International journal of pharmaceutics 2014-05, Vol.466 (1-2), p.341-348
Hauptverfasser:	Bahloul, Badr, Lassoued, Mohamed Ali, Sfar, Souad
Format:	Artikel
Sprache:	eng
Schlagworte:	Box–Behnken Drug Compounding Drug Delivery Systems Emulsions Fenofibrate Fenofibrate - chemistry HLB Hydrophobic and Hydrophilic Interactions Optimization SEDDS Solvents - chemistry Surface-Active Agents - chemistry
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