Influence of chronic ethanol intake on mouse synaptosomal aspartyl aminopeptidase and aminopeptidase A: Relationship with oxidative stress indicators

Abstract Aminopeptidase A (APA) and aspartyl aminopeptidase (ASAP) not only act as neuromodulators in the regional brain renin-angiotensin system, but also release N-terminal acidic amino acids (glutamate and aspartate). The hyperexcitability of amino acid neurotransmitters is responsible for severa...

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Veröffentlicht in:	Alcohol (Fayetteville, N.Y.) N.Y.), 2012-08, Vol.46 (5), p.481-487
Hauptverfasser:	Mayas, María Dolores, Ramírez-Expósito, María Jesús, García, María Jesús, Carrera, María Pilar, Martínez-Martos, José Manuel
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Drinking - physiopathology Aminopeptidase A Animals Aspartate aminopeptidase Chronic illnesses Colleges & universities Drinking water Ethanol Ethanol - pharmacology Glutamyl Aminopeptidase - metabolism Lipid Peroxidation - drug effects Lipids Male Mice Mice, Inbred BALB C Neurodegeneration Oxidative stress Oxidative Stress - drug effects Potassium - pharmacology Proteins Psychiatry Sucrose Synaptosomes - drug effects Synaptosomes - enzymology
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