Synergistic inhibition of Streptococcal biofilm by ribose and xylitol

Highlights • Biofilm formation of xylitol-resistant S. mutans was greater than that of normal S. mutans. • Ribose attenuated the increase of xylitol-resistant streptococcal biofilm. • Ribose may be effective to solve the problems evoked by continuous exposure to xylitol.

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Veröffentlicht in:Archives of oral biology 2015-02, Vol.60 (2), p.304-312
Hauptverfasser: Lee, Heon-Jin, Kim, Se Chul, Kim, Jinkyung, Do, Aejin, Han, Se Yeong, Lee, Bhumgey David, Lee, Hyun Ho, Lee, Min Chan, Lee, So Hui, Oh, Taejun, Park, Sangbin, Hong, Su-Hyung
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container_end_page 312
container_issue 2
container_start_page 304
container_title Archives of oral biology
container_volume 60
creator Lee, Heon-Jin
Kim, Se Chul
Kim, Jinkyung
Do, Aejin
Han, Se Yeong
Lee, Bhumgey David
Lee, Hyun Ho
Lee, Min Chan
Lee, So Hui
Oh, Taejun
Park, Sangbin
Hong, Su-Hyung
description Highlights • Biofilm formation of xylitol-resistant S. mutans was greater than that of normal S. mutans. • Ribose attenuated the increase of xylitol-resistant streptococcal biofilm. • Ribose may be effective to solve the problems evoked by continuous exposure to xylitol.
doi_str_mv 10.1016/j.archoralbio.2014.11.004
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Advanced Basic Science
Biofilm
Biofilms - drug effects
Cell Survival
Dentistry
Drug Synergism
Gene Expression
Glucan-binding proteins
Humans
Real-Time Polymerase Chain Reaction
Reserpine - pharmacology
Ribose
Ribose - pharmacology
RNA, Bacterial - analysis
Streptococcus
Streptococcus mutans
Streptococcus mutans - drug effects
Streptococcus mutans - genetics
Streptococcus sobrinus
Streptococcus sobrinus - drug effects
Streptococcus sobrinus - genetics
Xylitol
Xylitol - pharmacology
title Synergistic inhibition of Streptococcal biofilm by ribose and xylitol
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