Stimulation of the mineralocorticoid receptor improves memory in young and elderly healthy individuals

Abstract Glucocorticoids play an important role in cognitive function and act on glucocorticoid receptors and mineralocorticoid receptors (MRs) in the brain. Previously, the blockade of the MR has been shown to impair visuospatial and working memory in healthy young men. Here, we investigated the ef...

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Veröffentlicht in:	Neurobiology of aging 2015-02, Vol.36 (2), p.919-924
Hauptverfasser:	Hinkelmann, Kim, Wingenfeld, Katja, Kuehl, Linn K, Fleischer, Juliane, Heuser, Isabella, Wiedemann, Klaus, Otte, Christian
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Cognition Cortisol Cross-Over Studies Double-Blind Method Female Fludrocortisone Fludrocortisone - pharmacology Humans Internal Medicine Male Memory Memory - drug effects Middle Aged Mineralocorticoid receptor Neurology Random Allocation Receptors, Mineralocorticoid - agonists Stimulation, Chemical Stress Young Adult
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