CT and pathological features of primary hepatic angiosarcoma

The objective of this study is to present the computed tomography (CT) findings and associated pathological features of eight cases of primary hepatic angiosarcoma (PHA). All cases were confirmed by pathology. After a CT scan of the upper abdomen, all cases of PHA underwent enhanced scans in the arterial phase, portal venous phase, and delayed phase to observe the CT manifestations. The surgical specimens were subjected to conventional hematoxylin-eosin staining and immunohistochemistry and observed under a microscope. The CT scans showed a large hypodense lesion with irregular necrotic areas or scattered hemorrhage in PHA patients, whist enhanced scans showed a progressive filling and necrotic area in the central part. There could be "sharpen rim perpendicular to pleura" and "pseudocapsule" signs at the edge. It might be helpful to improve the diagnosis through the above characteristic features.