High consumption of fructose rather than glucose promotes a diet-induced obese phenotype in Drosophila melanogaster

During the last 20 years, there has been a considerable scientific debate about the possible mechanisms of induction of metabolic disorders by reducing monosaccharides such as glucose or fructose. In this study, we report the metabolic rearrangement in response to consumption of these monosaccharide...

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Veröffentlicht in:	Comparative biochemistry and physiology. Part A, Molecular & integrative physiology Molecular & integrative physiology, 2015-02, Vol.180, p.75-85
Hauptverfasser:	Rovenko, Bohdana M., Perkhulyn, Natalia V., Gospodaryov, Dmytro V., Sanz, Alberto, Lushchak, Oleh V., Lushchak, Volodymyr I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Body composition Diet Drosophila melanogaster Drosophila melanogaster - metabolism Drosophila Proteins - biosynthesis Fructose Fructose - administration & dosage Fructose - metabolism Glucose Glucose - metabolism Humans Inhibitor of Apoptosis Proteins - biosynthesis Insulin/IGF signaling Lipid Metabolism - drug effects Models, Animal Obesity Obesity - chemically induced Obesity - metabolism Obesity - pathology
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