Molecular characterization of Plasmodium falciparum Bruno/CELF RNA binding proteins

•Two Bruno/CELF homologues identified in P. falciparum (PfCELF1 and PfCELF2).•PfCELF1 shows RNA binding activity by UV crosslink assay.•PfCELF1 shows dual cytoplasmic and nuclear localization.•Putative mRNA targets of PfCELF1 identified by microarray ribonomic profiling. The human malaria parasite P...

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Veröffentlicht in:	Molecular and biochemical parasitology 2014-11, Vol.198 (1), p.1-10
Hauptverfasser:	Wongsombat, Chayaphat, Aroonsri, Aiyada, Kamchonwongpaisan, Sumalee, Morgan, Hugh P., Walkinshaw, Malcolm D., Yuthavong, Yongyuth, Shaw, Philip J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Motifs Base Sequence Bruno/CELF Humans Malaria, Falciparum - parasitology Microarray Molecular Sequence Data PfCELF1 PfCELF2 PfDHFR-TS Plasmodium falciparum Plasmodium falciparum - chemistry Plasmodium falciparum - genetics Plasmodium falciparum - growth & development Plasmodium falciparum - metabolism Protein Binding Protozoan Proteins - chemistry Protozoan Proteins - genetics Protozoan Proteins - metabolism RNA-Binding Proteins - chemistry RNA-Binding Proteins - genetics RNA-Binding Proteins - metabolism
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