Phase-transition contrast nanocapsules triggered by low-intensity ultrasound
A polymeric nanocapsule encapsulated with 1,1,1,3,3-pentafluorobutane was developed, in which 2,2,3,3,4,4,4-heptafluoro-1-butyl groups were introduced to the polymer terminal for high loading of liquid fluorocarbon. In vitro experiments demonstrate that its liquid/gas-phase transition can be trigger...
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| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2014-12, Vol.50 (96), p.15163-15166 |
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| container_issue | 96 |
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| container_title | Chemical communications (Cambridge, England) |
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| creator | Li, Hao Wang, Jianhao Wang, Ping Zheng, Jian Song, Fangfang Yin, Tinghui Zhou, Guofu Zheng, Rongqing Zhang, Chao |
| description | A polymeric nanocapsule encapsulated with 1,1,1,3,3-pentafluorobutane was developed, in which 2,2,3,3,4,4,4-heptafluoro-1-butyl groups were introduced to the polymer terminal for high loading of liquid fluorocarbon. In vitro experiments demonstrate that its liquid/gas-phase transition can be triggered by mild heating. This nanocapsule can be harnessed as a contrast agent for tumor imaging under diagnostic ultrasound. |
| doi_str_mv | 10.1039/c4cc04641b |
| format | Article |
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In vitro experiments demonstrate that its liquid/gas-phase transition can be triggered by mild heating. This nanocapsule can be harnessed as a contrast agent for tumor imaging under diagnostic ultrasound.</description><identifier>ISSN: 1359-7345</identifier><identifier>EISSN: 1364-548X</identifier><identifier>DOI: 10.1039/c4cc04641b</identifier><identifier>PMID: 25333624</identifier><language>eng</language><publisher>England</publisher><subject>Contrast agents ; Contrast Media - chemistry ; Diagnostic systems ; Encapsulation ; Fluorocarbons - chemistry ; Gases - chemistry ; Heating ; Humans ; Liquids ; Nanocapsules - chemistry ; Nanostructure ; Neoplasms - diagnosis ; Neoplasms - diagnostic imaging ; Phase Transition ; Polymers - chemistry ; Terminals ; Ultrasonography ; Ultrasound</subject><ispartof>Chemical communications (Cambridge, England), 2014-12, Vol.50 (96), p.15163-15166</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c320t-95b316b56ff7c6ee5ae1152d7a01052f187a0fc292813cf847ba87bedc6a965f3</citedby><cites>FETCH-LOGICAL-c320t-95b316b56ff7c6ee5ae1152d7a01052f187a0fc292813cf847ba87bedc6a965f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25333624$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Li, Hao</creatorcontrib><creatorcontrib>Wang, Jianhao</creatorcontrib><creatorcontrib>Wang, Ping</creatorcontrib><creatorcontrib>Zheng, Jian</creatorcontrib><creatorcontrib>Song, Fangfang</creatorcontrib><creatorcontrib>Yin, Tinghui</creatorcontrib><creatorcontrib>Zhou, Guofu</creatorcontrib><creatorcontrib>Zheng, Rongqing</creatorcontrib><creatorcontrib>Zhang, Chao</creatorcontrib><title>Phase-transition contrast nanocapsules triggered by low-intensity ultrasound</title><title>Chemical communications (Cambridge, England)</title><addtitle>Chem Commun (Camb)</addtitle><description>A polymeric nanocapsule encapsulated with 1,1,1,3,3-pentafluorobutane was developed, in which 2,2,3,3,4,4,4-heptafluoro-1-butyl groups were introduced to the polymer terminal for high loading of liquid fluorocarbon. In vitro experiments demonstrate that its liquid/gas-phase transition can be triggered by mild heating. This nanocapsule can be harnessed as a contrast agent for tumor imaging under diagnostic ultrasound.</description><subject>Contrast agents</subject><subject>Contrast Media - chemistry</subject><subject>Diagnostic systems</subject><subject>Encapsulation</subject><subject>Fluorocarbons - chemistry</subject><subject>Gases - chemistry</subject><subject>Heating</subject><subject>Humans</subject><subject>Liquids</subject><subject>Nanocapsules - chemistry</subject><subject>Nanostructure</subject><subject>Neoplasms - diagnosis</subject><subject>Neoplasms - diagnostic imaging</subject><subject>Phase Transition</subject><subject>Polymers - chemistry</subject><subject>Terminals</subject><subject>Ultrasonography</subject><subject>Ultrasound</subject><issn>1359-7345</issn><issn>1364-548X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkEtLxDAUhYMozji68QdIlyJU82661OILCrpQcFfS9GasdJIxaZH597bO6Nq7uefAd87iIHRK8CXBLL8y3BjMJSf1HpoTJnkquHrbn7TI04xxMUNHMX7g8YhQh2hGBWNMUj5H5fO7jpD2QbvY9q13ifFudLFPnHbe6HUcOohJH9rlEgI0Sb1JOv-Vtq6HKbJJhm7i_eCaY3RgdRfhZPcX6PXu9qV4SMun-8fiukwNo7hPc1EzImshrc2MBBAaCBG0yTQmWFBL1KisoTlVhBmreFZrldXQGKlzKSxboPNt7zr4zwFiX63aaKDrtAM_xIpIifGYztQ_UEqxkEryEb3Yoib4GAPYah3alQ6biuBqGroqeFH8DH0zwme73qFeQfOH_i7LvgE9K3lm</recordid><startdate>20141214</startdate><enddate>20141214</enddate><creator>Li, Hao</creator><creator>Wang, Jianhao</creator><creator>Wang, Ping</creator><creator>Zheng, Jian</creator><creator>Song, Fangfang</creator><creator>Yin, Tinghui</creator><creator>Zhou, Guofu</creator><creator>Zheng, Rongqing</creator><creator>Zhang, Chao</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7SP</scope><scope>7U5</scope><scope>8FD</scope><scope>L7M</scope></search><sort><creationdate>20141214</creationdate><title>Phase-transition contrast nanocapsules triggered by low-intensity ultrasound</title><author>Li, Hao ; 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| fulltext | fulltext |
| identifier | ISSN: 1359-7345 |
| ispartof | Chemical communications (Cambridge, England), 2014-12, Vol.50 (96), p.15163-15166 |
| issn | 1359-7345 1364-548X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1660092878 |
| source | MEDLINE; Royal Society Of Chemistry Journals; Alma/SFX Local Collection |
| subjects | Contrast agents Contrast Media - chemistry Diagnostic systems Encapsulation Fluorocarbons - chemistry Gases - chemistry Heating Humans Liquids Nanocapsules - chemistry Nanostructure Neoplasms - diagnosis Neoplasms - diagnostic imaging Phase Transition Polymers - chemistry Terminals Ultrasonography Ultrasound |
| title | Phase-transition contrast nanocapsules triggered by low-intensity ultrasound |
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