$Local drug delivery for enhancing fracture healing in osteoporotic bone$

Local drug delivery for enhancing fracture healing in osteoporotic bone

[Display omitted] Fragility fractures can cause significant morbidity and mortality in patients with osteoporosis and inflict a considerable medical and socioeconomic burden. Moreover, treatment of an osteoporotic fracture is challenging due to the decreased strength of the surrounding bone and subo...

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Veröffentlicht in:	Acta biomaterialia 2015-01, Vol.11, p.412-434
Hauptverfasser:	Kyllönen, Laura, D’Este, Matteo, Alini, Mauro, Eglin, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatibility Biomedical materials Bone Morphogenetic Protein 2 - administration & dosage Bone Morphogenetic Protein 2 - chemistry Bones Drug delivery Drug delivery systems Drug Implants - administration & dosage Drug Implants - chemical synthesis Fibroblast Growth Factor 2 - administration & dosage Fibroblast Growth Factor 2 - chemistry Formations Fracture Healing - drug effects Fracture Healing - physiology Fracture mechanics Growth factors Healing Humans Nanocapsules - administration & dosage Nanocapsules - chemistry Nanocapsules - ultrastructure Osteoporosis Osteoporotic fracture Osteoporotic Fractures - drug therapy Osteoporotic Fractures - physiopathology Small molecules
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