Reduction of suture associated inflammation after 28 days using novel biocompatible pseudoprotein poly(ester amide) biomaterials

Sutures elicit an inflammatory response, which may impede the healing process and result in wound complications. We recently reported a novel family of biocompatible, biodegradable polymers, amino acid-based poly(ester amide)s (AA-PEA), which we have shown to significantly attenuate the foreign body...

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Veröffentlicht in:	Journal of biomedical materials research. Part B, Applied biomaterials Applied biomaterials, 2015-02, Vol.103 (2), p.457-463
Hauptverfasser:	Hernandez, Karina A., Hooper, Rachel Campbell, Boyko, Tatiana, Golas, Alyssa R., van Harten, Michel, Wu, D.Q., Weinstein, Andrew, Chu, C.C., Spector, Jason A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biocompatibility Biodegradable Plastics - pharmacology Biomaterials Biomedical materials Coated Materials, Biocompatible - pharmacology Coating foreign body Foreign-Body Reaction - etiology Foreign-Body Reaction - prevention & control inflammation Inflammatory response Male Materials research Materials science Mice polyesteramide amino acid Polyesters - pharmacology Silk Silk - pharmacology Surgical implants suture Sutures Sutures - adverse effects
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