A fast and simple procedure for determination of perfluoroalkyl substances in food and feed: a method verification by an interlaboratory study
In this study, a simple, fast, and cheap sample preparation procedure for the analysis of three well-known representatives of perfluoroalkyl substances (perfluorooctane sulfonate, perfluorooctanoic acid, and perfluorooctane sulfonamide) was validated in accordance with Commission Decision 2002/657/E...
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| Veröffentlicht in: | Analytical and bioanalytical chemistry 2013-09, Vol.405 (24), p.7817-7827 |
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| creator | Hrádková, P. Poustka, J. Pulkrabová, J. Hlousková, V. Kocourek, V. Llorca, M. Farré, M. Barceló, D. Hajslová, J. |
| description | In this study, a simple, fast, and cheap sample preparation procedure for the analysis of three well-known representatives of perfluoroalkyl substances (perfluorooctane sulfonate, perfluorooctanoic acid, and perfluorooctane sulfonamide) was validated in accordance with Commission Decision 2002/657/EC. The method was based on extraction with methanol followed by a dispersive solid phase extraction cleanup step by addition of activated charcoal for fish tissue, fish feed, and milk samples. The novel analytical approach combined with liquid chromatography–tandem mass spectrometry makes it possible to achieve limits of quantification below 1 μg/kg (defined by Commission Recommendation 2010/161/EU). This method provides a high laboratory sample throughput: ten samples in 60 min. The validated procedure was successfully verified in an interlaboratory study. |
| doi_str_mv | 10.1007/s00216-013-6962-6 |
| format | Article |
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The method was based on extraction with methanol followed by a dispersive solid phase extraction cleanup step by addition of activated charcoal for fish tissue, fish feed, and milk samples. The novel analytical approach combined with liquid chromatography–tandem mass spectrometry makes it possible to achieve limits of quantification below 1 μg/kg (defined by Commission Recommendation 2010/161/EU). This method provides a high laboratory sample throughput: ten samples in 60 min. The validated procedure was successfully verified in an interlaboratory study.</description><identifier>ISSN: 1618-2642</identifier><identifier>EISSN: 1618-2650</identifier><identifier>DOI: 10.1007/s00216-013-6962-6</identifier><identifier>PMID: 23609786</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Acids ; Activated charcoal ; Analytical Chemistry ; Animal tissues ; Biochemistry ; Characterization and Evaluation of Materials ; Charcoal ; Chemical properties ; Chemistry ; Chemistry and Materials Science ; Chromatography ; Extraction ; Fish ; Fish feeds ; Food ; Food Science ; Foods ; Identification and classification ; Interlaboratory ; Laboratories ; Laboratory Medicine ; Liquid chromatography ; Liquids ; Mass spectrometry ; Mathematical analysis ; Methods ; Methyl alcohol ; Monitoring/Environmental Analysis ; Perfluoroalkyl & polyfluoroalkyl substances ; Perfluoroalkyls ; Perfluorocarbons ; Perfluorooctanoic acid ; Rapid Detection in Food and Feed ; Research Paper ; Sample preparation ; Scientific imaging ; Testing</subject><ispartof>Analytical and bioanalytical chemistry, 2013-09, Vol.405 (24), p.7817-7827</ispartof><rights>Springer-Verlag Berlin Heidelberg 2013</rights><rights>COPYRIGHT 2013 Springer</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c444t-a5389e8ef895f14a1b7dedf4de56a0c1b222a4dc5f195edb35c66cf15878f4813</citedby><cites>FETCH-LOGICAL-c444t-a5389e8ef895f14a1b7dedf4de56a0c1b222a4dc5f195edb35c66cf15878f4813</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00216-013-6962-6$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00216-013-6962-6$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,778,782,27907,27908,41471,42540,51302</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23609786$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hrádková, P.</creatorcontrib><creatorcontrib>Poustka, J.</creatorcontrib><creatorcontrib>Pulkrabová, J.</creatorcontrib><creatorcontrib>Hlousková, V.</creatorcontrib><creatorcontrib>Kocourek, V.</creatorcontrib><creatorcontrib>Llorca, M.</creatorcontrib><creatorcontrib>Farré, M.</creatorcontrib><creatorcontrib>Barceló, D.</creatorcontrib><creatorcontrib>Hajslová, J.</creatorcontrib><title>A fast and simple procedure for determination of perfluoroalkyl substances in food and feed: a method verification by an interlaboratory study</title><title>Analytical and bioanalytical chemistry</title><addtitle>Anal Bioanal Chem</addtitle><addtitle>Anal Bioanal Chem</addtitle><description>In this study, a simple, fast, and cheap sample preparation procedure for the analysis of three well-known representatives of perfluoroalkyl substances (perfluorooctane sulfonate, perfluorooctanoic acid, and perfluorooctane sulfonamide) was validated in accordance with Commission Decision 2002/657/EC. 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The validated procedure was successfully verified in an interlaboratory study.</description><subject>Acids</subject><subject>Activated charcoal</subject><subject>Analytical Chemistry</subject><subject>Animal tissues</subject><subject>Biochemistry</subject><subject>Characterization and Evaluation of Materials</subject><subject>Charcoal</subject><subject>Chemical properties</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Chromatography</subject><subject>Extraction</subject><subject>Fish</subject><subject>Fish feeds</subject><subject>Food</subject><subject>Food Science</subject><subject>Foods</subject><subject>Identification and classification</subject><subject>Interlaboratory</subject><subject>Laboratories</subject><subject>Laboratory Medicine</subject><subject>Liquid chromatography</subject><subject>Liquids</subject><subject>Mass spectrometry</subject><subject>Mathematical analysis</subject><subject>Methods</subject><subject>Methyl alcohol</subject><subject>Monitoring/Environmental Analysis</subject><subject>Perfluoroalkyl & polyfluoroalkyl substances</subject><subject>Perfluoroalkyls</subject><subject>Perfluorocarbons</subject><subject>Perfluorooctanoic acid</subject><subject>Rapid Detection in Food and Feed</subject><subject>Research Paper</subject><subject>Sample preparation</subject><subject>Scientific 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perfluoroalkyl substances (perfluorooctane sulfonate, perfluorooctanoic acid, and perfluorooctane sulfonamide) was validated in accordance with Commission Decision 2002/657/EC. The method was based on extraction with methanol followed by a dispersive solid phase extraction cleanup step by addition of activated charcoal for fish tissue, fish feed, and milk samples. The novel analytical approach combined with liquid chromatography–tandem mass spectrometry makes it possible to achieve limits of quantification below 1 μg/kg (defined by Commission Recommendation 2010/161/EU). This method provides a high laboratory sample throughput: ten samples in 60 min. The validated procedure was successfully verified in an interlaboratory study.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>23609786</pmid><doi>10.1007/s00216-013-6962-6</doi><tpages>11</tpages></addata></record> |
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| subjects | Acids Activated charcoal Analytical Chemistry Animal tissues Biochemistry Characterization and Evaluation of Materials Charcoal Chemical properties Chemistry Chemistry and Materials Science Chromatography Extraction Fish Fish feeds Food Food Science Foods Identification and classification Interlaboratory Laboratories Laboratory Medicine Liquid chromatography Liquids Mass spectrometry Mathematical analysis Methods Methyl alcohol Monitoring/Environmental Analysis Perfluoroalkyl & polyfluoroalkyl substances Perfluoroalkyls Perfluorocarbons Perfluorooctanoic acid Rapid Detection in Food and Feed Research Paper Sample preparation Scientific imaging Testing |
| title | A fast and simple procedure for determination of perfluoroalkyl substances in food and feed: a method verification by an interlaboratory study |
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