Fabrication of injectable, cellular, anisotropic collagen tissue equivalents with modular fibrillar densities

Abstract Technological improvements in collagen gel fabrication are highly desirable as they may enable significant advances in the formation of tissue-equivalent biomaterials for regenerative medicine, three-dimensional (3D) in vitro tissue models, and injectable scaffolds for cell and drug deliver...

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Veröffentlicht in:	Biomaterials 2015-01, Vol.37, p.183-193
Hauptverfasser:	Marelli, Benedetto, Ghezzi, Chiara E, James-Bhasin, Mark, Nazhat, Showan N
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Animals Anisotropy Biocompatibility Biocompatible Materials - pharmacology Biomedical materials Cell Transdifferentiation - drug effects Cells, Cultured Collagen - pharmacology Collagens Density Dentistry Differentiation Exposure Fibroblasts - cytology Fibroblasts - drug effects Fibroblasts - ultrastructure Gels Gene Expression Regulation - drug effects Injections Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - drug effects Mesenchymal Stromal Cells - metabolism Mesenchymal Stromal Cells - ultrastructure Mice Nanoparticles - ultrastructure Neurons - cytology Neurons - drug effects NIH 3T3 Cells Osteoblasts - cytology Osteoblasts - drug effects Osteoblasts - metabolism Osteogenesis - drug effects Rats Three dimensional
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