Osteogenic potency of magnetic fibrin nanoparticles—A novel perspective in bone tissue engineering

In the present study, goat blood has been used as the starting material for the preparation of novel magnetic fibrin nanoparticles (MAG-FNPs) in tissue engineering. The synthesised nanoparticles were characterized by X-ray diffractometer (XRD), transmittance electron microscope (TEM), scanning electron microscope (SEM), Fourier Transform Infrared spectroscopy (FTIR), energy dispersive X-ray spectroscopy (EDX) and vibrating sample magnetometer (VSM) analysis. The osteogenic potential of MAG-FNPs was evaluated by performing cell viability assay and quantifying alkaline phosphatase (ALP) levels using Saos-2 cells. The results obtained suggested that MAG-FNPs could serve as promising biomaterial for bone tissue engineering.