Mammary gland morphology and responsiveness to regulatory molecules following prenatal exposure to diethylstilbestrol

Female ACI rats were exposed to diethylstilbestrol (DES) in utero to evaluate the effects on the peri‐pubertal mammary gland with respect to 1) mammary gland morphology, 2) sensitivity to natural and synthetic estrogens, and 3) sensitivity to endogenous epidermal growth factor (EGF). Pregnant rats w...

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Veröffentlicht in:	Teratogenesis, carcinogenesis, and mutagenesis carcinogenesis, and mutagenesis, 1993, Vol.13 (2), p.59-74
Hauptverfasser:	Vassilacopoulou, Dido, Boylan, Elizabeth S.
Format:	Artikel
Sprache:	eng
Schlagworte:	ACI rat Animals Biological and medical sciences Diethylstilbestrol - toxicity Drug toxicity and drugs side effects treatment Elvax pellet epidermal growth factor Estradiol - pharmacology estrogen Female Fetus - drug effects Mammary Glands, Animal - drug effects Mammary Glands, Animal - pathology mammary tumor Medical sciences Miscellaneous (drug allergy, mutagens, teratogens...) Pharmacology. Drug treatments Pregnancy Prenatal Exposure Delayed Effects Rats Rats, Inbred ACI sialoadenectomy Submandibular Gland - surgery
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