Angiotensin II-induced protein tyrosine phosphorylation in neonatal rat cardiac fibroblasts

Angiotensin II has been demonstrated to act as a growth factor in rat cardiac fibroblasts. However, the signaling events that lead to fibroblast cell growth in response to angiotensin II remain to be elucidated. This study was designed to determine whether angiotensin II stimulated tyrosine phosphor...

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Veröffentlicht in:	The Journal of biological chemistry 1994-07, Vol.269 (30), p.19626-19632
Hauptverfasser:	SCHORB, W, PEELER, T. C, MADIGAN, N. N, CONRAD, K. M, BAKER, K. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing Adaptor Proteins, Vesicular Transport Angiotensin II - pharmacology Animals Animals, Newborn Biological and medical sciences Calcium-Calmodulin-Dependent Protein Kinases - metabolism Cell Adhesion Molecules - metabolism Cell physiology Cells, Cultured Fibroblasts - drug effects Fibroblasts - metabolism Focal Adhesion Kinase 1 Focal Adhesion Protein-Tyrosine Kinases Fundamental and applied biological sciences. Psychology GTP-Binding Proteins - metabolism Mitogen-Activated Protein Kinase 3 Mitogen-Activated Protein Kinases Molecular and cellular biology Myocardium - cytology Myocardium - metabolism Phorbol Esters - pharmacology Phosphorylation Platelet-Derived Growth Factor - pharmacology Protein Kinase C - metabolism Protein-Tyrosine Kinases - metabolism Proteins - metabolism Rats Rats, Sprague-Dawley Responses to growth factors, tumor promotors, other factors Shc Signaling Adaptor Proteins Signal Transduction Src Homology 2 Domain-Containing, Transforming Protein 1 Tyrosine
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