The cortical epithelium of the rat thymus after in vivo exposure to bis(tri-n-butyltin)oxide (TBTO) : an (immuno)histological and ultrastructural study

Bis(tri-n-butyltin)oxide (TBTO) induces cortical atrophy in the rat thymus. We studied the potential involvement of the cortical epithelium in TBTO-induced thymotoxicity by (immuno) histology and electron microscopy. Juvenile male Wistar rats were orally intubated once with either 30 or 90 mg/kg TBT...

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Veröffentlicht in:	Archives of toxicology 1993, Vol.67 (3), p.186-192
Hauptverfasser:	DE WAAL, E. J, SCHUURMAN, H.-J, RADEMAKERS, L. H. P. M, VAN LOVEREN, H, VOS, J. G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Chemical and industrial products toxicology. Toxic occupational diseases Epithelium - drug effects Epithelium - pathology Epithelium - ultrastructure Immunohistochemistry Immunosuppressive Agents - pharmacology Immunosuppressive Agents - toxicity Male Medical sciences Metals and various inorganic compounds Microscopy, Electron Organ Size - drug effects Rats Rats, Wistar Thymus Gland - drug effects Thymus Gland - pathology Thymus Gland - ultrastructure Toxicology Trialkyltin Compounds - pharmacology Trialkyltin Compounds - toxicity
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