Interleukin 23 Levels Are Increased in Carotid Atherosclerosis: Possible Role for the Interleukin 23/Interleukin 17 Axis

BACKGROUND AND PURPOSE—Interleukin (IL)-23 is a cytokine in the IL-12 family, mainly produced by antigen-presenting cells with a central role in inflammation. We hypothesize that IL-23 is also important in atherogenesis and investigate this in a population with carotid atherosclerosis. METHODS—Plasm...

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Veröffentlicht in:	Stroke (1970) 2015-03, Vol.46 (3), p.793-799
Hauptverfasser:	Abbas, Azhar, Gregersen, Ida, Holm, Sverre, Daissormont, Isabelle, Bjerkeli, Vigdis, Krohg-Sørensen, Kirsten, Skagen, Karolina R, Dahl, Tuva B, Russell, David, Almås, Trine, Bundgaard, Dorte, Alteheld, Lars Holger, Rashidi, Azita, Dahl, Christen P, Michelsen, Annika E, Biessen, Erik A, Aukrust, Pål, Halvorsen, Bente, Skjelland, Mona
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Atherosclerosis - blood Atherosclerosis - metabolism Carotid Artery Diseases - blood Carotid Artery Diseases - metabolism Carotid Stenosis - blood Carotid Stenosis - metabolism Female Follow-Up Studies Gene Expression Regulation Humans Inflammation Interleukin-17 - blood Interleukin-23 - blood Leukocytes, Mononuclear - metabolism Male Middle Aged Plaque, Atherosclerotic - metabolism Receptors, Interleukin - blood RNA, Messenger - metabolism Stroke - blood
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