Genetic diversity of CYP3A4 and CYP3A5 polymorphisms in North African populations from Morocco and Tunisia

The genes CYP3A4 and CYP3A5 form part of a cluster of cytochrome P450 genes involved in drug metabolism reactions. The allelic variants of these genes CYP3A4*1B, CYP3A4*3, CYP3A4*17 and CYP3A5*3 have been linked both to the reduced catalytic activity of cytochromes and to prostate cancer risk in whi...

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Veröffentlicht in:	The International journal of biological markers 2015-01, Vol.30 (1), p.148-151
Hauptverfasser:	Novillo, Apolonia, Romero-Lorca, Alicia, Gaibar, María, Bahri, Raoudha, Harich, Nourdin, Sánchez-Cuenca, David, Esteban, Esther, Fernández-Santander, Ana
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cytochrome P-450 CYP3A - genetics Female Gene Frequency Haplotypes Humans Male Morocco Polymorphism, Single Nucleotide Sequence Analysis, DNA Tunisia
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