Rodent versus human insulitis: why the huge disconnect?

The purpose of this article is to summarize recent developments in the histopathology of recent-onset type 1 diabetes. Insulitis is considered to be the defining lesion in young type 1 diabetic patients, and insight into its pathogenic mechanism is crucial for the development of effective new therap...

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Veröffentlicht in:	Current opinion in endocrinology, diabetes, and obesity diabetes, and obesity, 2015-04, Vol.22 (2), p.86-90
1. Verfasser:	in’t Veld, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autoimmunity Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - diagnosis Diabetes Mellitus, Type 1 - immunology Diabetes Mellitus, Type 1 - physiopathology Disease Models, Animal Humans Mice, Inbred NOD Pancreas - immunology Pancreas - metabolism Pancreas - physiopathology Prognosis Species Specificity T-Lymphocytes - immunology T-Lymphocytes - metabolism Translational Medical Research
Online-Zugang:	Volltext
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