Renal effects of atorvastatin and rosuvastatin in patients with diabetes who have progressive renal disease (PLANET I): a randomised clinical trial

Summary Background The role of lipid-lowering treatments in renoprotection for patients with diabetes is debated. We studied the renal effects of two statins in patients with diabetes who had proteinuria. Methods PLANET I was a randomised, double-blind, parallel-group trial done in 147 research cent...

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Veröffentlicht in:	The lancet. Diabetes & endocrinology 2015-03, Vol.3 (3), p.181-190
Hauptverfasser:	de Zeeuw, Dick, Prof, Anzalone, Deborah A, MD, Cain, Valerie A, MS, Cressman, Michael D, DO, Heerspink, Hiddo J Lambers, PhD, Molitoris, Bruce A, Prof, Monyak, John T, PhD, Parving, Hans-Henrik, Prof, Remuzzi, Giuseppe, Prof, Sowers, James R, Prof, Vidt, Donald G, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis of Variance Angiotensin Receptor Antagonists - therapeutic use Angiotensin-Converting Enzyme Inhibitors - therapeutic use Atorvastatin Calcium Creatinine - urine Diabetes Complications - drug therapy Diabetic Nephropathies - drug therapy Dose-Response Relationship, Drug Double-Blind Method Endocrinology & Metabolism Europe Fluorobenzenes - pharmacology Fluorobenzenes - therapeutic use Heptanoic Acids - pharmacology Heptanoic Acids - therapeutic use Humans Kidney - drug effects Lipids - blood North America Other Proteinuria Pyrimidines - pharmacology Pyrimidines - therapeutic use Pyrroles - pharmacology Pyrroles - therapeutic use Rosuvastatin Calcium South America Sulfonamides - pharmacology Sulfonamides - therapeutic use
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