A colorimetric lead (II) ions sensor based on selective recognition of G-quadruplexes by a clip-like cyanine dye

A probe for colorimetric detecting lead ion (Pb2+) has been designed by using a newly synthesized clip-like cyanine dye and G-quadruplex. The unique structure of the clip-like cyanine dye endowed the probe with a high selectivity towards Pb2+. Significant changes in absorption spectra of the cyanine...

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Veröffentlicht in:Talanta (Oxford) 2015-05, Vol.136, p.210-214
Hauptverfasser: Sun, Hongxia, Yu, Lijia, Chen, Hongbo, Xiang, Junfeng, Zhang, Xiufeng, Shi, Yunhua, Yang, Qianfan, Guan, Aijiao, Li, Qian, Tang, Yalin
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container_title Talanta (Oxford)
container_volume 136
creator Sun, Hongxia
Yu, Lijia
Chen, Hongbo
Xiang, Junfeng
Zhang, Xiufeng
Shi, Yunhua
Yang, Qianfan
Guan, Aijiao
Li, Qian
Tang, Yalin
description A probe for colorimetric detecting lead ion (Pb2+) has been designed by using a newly synthesized clip-like cyanine dye and G-quadruplex. The unique structure of the clip-like cyanine dye endowed the probe with a high selectivity towards Pb2+. Significant changes in absorption spectra of the cyanine dye recognizing the Pb2+-induced conformational transition of G-quadruplexes made the probe show a high sensitivity towards Pb2+ with a detection limit of 1nM. The excellent performance enabled the probe to be practically applied in measuring the Pb2+ pollution in freshwater system. [Display omitted] •A probe is designed for colorimetric detection of Pb2+.•A clip-like cyanine dye is synthesized.•The dye can recognize Pb2+-induced G-quadruplex transition.•The probe shows a high specificity and sensitivity.•Detection of the Pb2+ in freshwater system is applied.
doi_str_mv 10.1016/j.talanta.2015.01.027
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subjects A clip-like cyanine dye
Colorimetric detection
Colorimetry
Coloring Agents - chemistry
G-quadruplex
G-Quadruplexes
Lead (II) ion
Lead - analysis
Practical application
title A colorimetric lead (II) ions sensor based on selective recognition of G-quadruplexes by a clip-like cyanine dye
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