Blocking the Peroxisome Proliferator-Activated Receptor (PPAR): An Overview

Peroxisome proliferator‐activated receptors (PPARs) have been studied extensively over the last few decades and have been assessed as molecular targets for the development of drugs against metabolic disorders. A rapid increase in understanding of the physiology and pharmacology of these receptors ha...

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Veröffentlicht in:	ChemMedChem 2013-10, Vol.8 (10), p.1609-1616
Hauptverfasser:	Ammazzalorso, Alessandra, De Filippis, Barbara, Giampietro, Letizia, Amoroso, Rosa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals antagonists Humans Indoles - chemistry Indoles - metabolism isoform selectivity Metabolic disorders Peroxisome Proliferator-Activated Receptors - antagonists & inhibitors Peroxisome Proliferator-Activated Receptors - metabolism PPARs Protein Binding Protein Isoforms - antagonists & inhibitors Protein Isoforms - metabolism receptors Structure-Activity Relationship structure-activity relationships Thiazolidinediones - chemistry Thiazolidinediones - metabolism Thiophenes - chemistry Thiophenes - metabolism
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