Altered cytotoxicity of (2-chloroethyl)-3-sarcosinamide-1-nitrosourea in human glioma cell lines SK-MG-1 and SKI-1 correlates with differential transport kinetics

Resistance to (2-chloroethyl)-3-sarcosinamide-1-nitrosourea (SarCNU), an experimental anticancer compound, was investigated in the chloroethylnitrosourea-sensitive Mer- SK-MG-1 and -resistant Mer- SKI-1 human glioma cell lines. The transport of [3H]SarCNU was examined in suspension. The uptake of [3...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1994-03, Vol.54 (6), p.1491-1496
Hauptverfasser:	NOË, A. J, MALAPETSA, A, PANASCI, L. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Antineoplastic Agents - metabolism Antineoplastic Agents - pharmacokinetics Antineoplastic Agents - toxicity Biological and medical sciences Biological Transport Carmustine - analogs & derivatives Carmustine - metabolism Carmustine - pharmacokinetics Carmustine - toxicity Chromatography, Thin Layer General aspects Glioma - drug therapy Glioma - metabolism Humans Kinetics Medical sciences Pharmacology. Drug treatments Temperature Tritium Tumor Cells, Cultured - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!