Proprotein convertase subtilisin/kexin type 9 (PCSK9) and inhibitors

Hypercholesterolemia is a major risk factor for atherosclerosis. Low-density lipoprotein cholesterol (LDL-C) lowering drugs reduce cardiovascular morbidity and mortality. However, many individuals treated with statins do not achieve their target levels of LDL-C. So, there is great need for new drugs...

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Veröffentlicht in:	Türk Kardiyoloji Derneği arşivi 2014-10, Vol.42 Suppl 2, p.56-67
Hauptverfasser:	Avci, Ahmet, Demir, Kenan, Altunkeser, Bülent Behlül
Format:	Artikel
Sprache:	tur
Schlagworte:	Antibodies, Monoclonal - therapeutic use Anticholesteremic Agents - therapeutic use Cholesterol, LDL - blood Humans Hypercholesterolemia - blood Hypercholesterolemia - drug therapy Proprotein Convertase 9 Proprotein Convertases - metabolism Serine Endopeptidases - metabolism
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