The evolving genomic landscape of myeloproliferative neoplasms

Our understanding of the genetic basis of the Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs) has moved forward at a staggering pace over the last decade. With the discoveries of underlying mutations in JAK2, MPL, and, most recently, calreticulin (CALR), that together account fo...

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Veröffentlicht in:	Hematology 2014-12, Vol.2014 (1), p.287-296
Hauptverfasser:	Nangalia, Jyoti, Green, Tony R
Format:	Artikel
Sprache:	eng
Schlagworte:	Epigenesis, Genetic Genetic Predisposition to Disease Genome, Human Humans Mutation - genetics Myeloproliferative Disorders - genetics Myeloproliferative Disorders - pathology RNA Splicing - genetics
Online-Zugang:	Volltext
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