The frozen elephant trunk technique for the treatment of complicated type B aortic dissection with involvement of the aortic arch: multicentre early experience
Providing effective treatment for complicated type B aortic dissection (AD) with concomitant pathologies of the aortic arch or ascending aorta is challenging, especially if the aortic anatomy is contraindicated for thoracic endovascular aortic repair (TEVAR). We present the early results of a multic...
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Veröffentlicht in: | European journal of cardio-thoracic surgery 2015-01, Vol.47 (1), p.106-114 |
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container_title | European journal of cardio-thoracic surgery |
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creator | Weiss, Gabriel Tsagakis, Konstantinos Jakob, Heinz Di Bartolomeo, Roberto Pacini, Davide Barberio, Giuseppe Mascaro, Jorge Mestres, Carlos-A Sioris, Thanos Grabenwoger, Martin |
description | Providing effective treatment for complicated type B aortic dissection (AD) with concomitant pathologies of the aortic arch or ascending aorta is challenging, especially if the aortic anatomy is contraindicated for thoracic endovascular aortic repair (TEVAR). We present the early results of a multicentre study using the frozen elephant trunk (FET) technique for type B AD.
From January 2005 to March 2013, data from 465 patients who had undergone treatment with the FET technique were collected in the database of the International E-vita Open Registry. From this cohort, 57 patients who had a primary indication for surgery for type B AD were included in the present study. Their mean age was 58±12 years, and 72% had a chronic dissection. All operations were performed in circulatory arrest and bilateral antegrade cerebral perfusion. Computed aortic imaging was performed for false lumen (FL) evaluation during the follow-up.
The in-hospital mortality rate was 14% (8/57). Stroke and spinal cord injury occurred in 6 (10%) and 2 patients (4%), respectively. The rate of immediate FL thrombosis at the level of the stent graft was 75% (40/53) and increased to 97% (41/42) during the follow-up period (23±19 months). Distally, at the level of the abdominal aorta, the FL remained patent in 50% (21/42) of patients. The 1- and 3-year survival was 81 and 75%, respectively.
The FET technique is a feasible therapeutic option for complicated type B AD with involvement of the aortic arch if TEVAR is contraindicated. In contrast to conventional aortic surgery via a lateral thoracotomy, the FET procedure can provide simultaneous treatment of the ascending aorta and aortic arch. |
doi_str_mv | 10.1093/ejcts/ezu067 |
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From January 2005 to March 2013, data from 465 patients who had undergone treatment with the FET technique were collected in the database of the International E-vita Open Registry. From this cohort, 57 patients who had a primary indication for surgery for type B AD were included in the present study. Their mean age was 58±12 years, and 72% had a chronic dissection. All operations were performed in circulatory arrest and bilateral antegrade cerebral perfusion. Computed aortic imaging was performed for false lumen (FL) evaluation during the follow-up.
The in-hospital mortality rate was 14% (8/57). Stroke and spinal cord injury occurred in 6 (10%) and 2 patients (4%), respectively. The rate of immediate FL thrombosis at the level of the stent graft was 75% (40/53) and increased to 97% (41/42) during the follow-up period (23±19 months). Distally, at the level of the abdominal aorta, the FL remained patent in 50% (21/42) of patients. The 1- and 3-year survival was 81 and 75%, respectively.
The FET technique is a feasible therapeutic option for complicated type B AD with involvement of the aortic arch if TEVAR is contraindicated. In contrast to conventional aortic surgery via a lateral thoracotomy, the FET procedure can provide simultaneous treatment of the ascending aorta and aortic arch.</description><identifier>ISSN: 1010-7940</identifier><identifier>EISSN: 1873-734X</identifier><identifier>DOI: 10.1093/ejcts/ezu067</identifier><identifier>PMID: 24599159</identifier><language>eng</language><publisher>Germany</publisher><subject>Adult ; Aged ; Aneurysm, Dissecting - epidemiology ; Aneurysm, Dissecting - mortality ; Aneurysm, Dissecting - surgery ; Aorta, Thoracic - surgery ; Aortic Aneurysm, Thoracic - epidemiology ; Aortic Aneurysm, Thoracic - mortality ; Aortic Aneurysm, Thoracic - surgery ; Blood Vessel Prosthesis Implantation - adverse effects ; Blood Vessel Prosthesis Implantation - methods ; Female ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged</subject><ispartof>European journal of cardio-thoracic surgery, 2015-01, Vol.47 (1), p.106-114</ispartof><rights>The Author 2014. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c329t-f5d94e68794a073a17c765b5fe66b819fbf31f14ae2b75128bb12b809300149a3</citedby><cites>FETCH-LOGICAL-c329t-f5d94e68794a073a17c765b5fe66b819fbf31f14ae2b75128bb12b809300149a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24599159$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Weiss, Gabriel</creatorcontrib><creatorcontrib>Tsagakis, Konstantinos</creatorcontrib><creatorcontrib>Jakob, Heinz</creatorcontrib><creatorcontrib>Di Bartolomeo, Roberto</creatorcontrib><creatorcontrib>Pacini, Davide</creatorcontrib><creatorcontrib>Barberio, Giuseppe</creatorcontrib><creatorcontrib>Mascaro, Jorge</creatorcontrib><creatorcontrib>Mestres, Carlos-A</creatorcontrib><creatorcontrib>Sioris, Thanos</creatorcontrib><creatorcontrib>Grabenwoger, Martin</creatorcontrib><title>The frozen elephant trunk technique for the treatment of complicated type B aortic dissection with involvement of the aortic arch: multicentre early experience</title><title>European journal of cardio-thoracic surgery</title><addtitle>Eur J Cardiothorac Surg</addtitle><description>Providing effective treatment for complicated type B aortic dissection (AD) with concomitant pathologies of the aortic arch or ascending aorta is challenging, especially if the aortic anatomy is contraindicated for thoracic endovascular aortic repair (TEVAR). We present the early results of a multicentre study using the frozen elephant trunk (FET) technique for type B AD.
From January 2005 to March 2013, data from 465 patients who had undergone treatment with the FET technique were collected in the database of the International E-vita Open Registry. From this cohort, 57 patients who had a primary indication for surgery for type B AD were included in the present study. Their mean age was 58±12 years, and 72% had a chronic dissection. All operations were performed in circulatory arrest and bilateral antegrade cerebral perfusion. Computed aortic imaging was performed for false lumen (FL) evaluation during the follow-up.
The in-hospital mortality rate was 14% (8/57). Stroke and spinal cord injury occurred in 6 (10%) and 2 patients (4%), respectively. The rate of immediate FL thrombosis at the level of the stent graft was 75% (40/53) and increased to 97% (41/42) during the follow-up period (23±19 months). Distally, at the level of the abdominal aorta, the FL remained patent in 50% (21/42) of patients. The 1- and 3-year survival was 81 and 75%, respectively.
The FET technique is a feasible therapeutic option for complicated type B AD with involvement of the aortic arch if TEVAR is contraindicated. In contrast to conventional aortic surgery via a lateral thoracotomy, the FET procedure can provide simultaneous treatment of the ascending aorta and aortic arch.</description><subject>Adult</subject><subject>Aged</subject><subject>Aneurysm, Dissecting - epidemiology</subject><subject>Aneurysm, Dissecting - mortality</subject><subject>Aneurysm, Dissecting - surgery</subject><subject>Aorta, Thoracic - surgery</subject><subject>Aortic Aneurysm, Thoracic - epidemiology</subject><subject>Aortic Aneurysm, Thoracic - mortality</subject><subject>Aortic Aneurysm, Thoracic - surgery</subject><subject>Blood Vessel Prosthesis Implantation - adverse effects</subject><subject>Blood Vessel Prosthesis Implantation - methods</subject><subject>Female</subject><subject>Humans</subject><subject>Kaplan-Meier Estimate</subject><subject>Male</subject><subject>Middle Aged</subject><issn>1010-7940</issn><issn>1873-734X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kctOwzAQRS0Eorx2rJGXLAjYcRLH7KDiJSGxAYld5LhjxSWJg-0U2p_hVzG0sJoZzZkr3bkIHVNyTolgFzBXwV_AaiQF30J7tOQs4Sx73Y49oSThIiMTtO_9nBBSsJTvokma5ULQXOyhr-cGsHZ2BT2GFoZG9gEHN_ZvOIBqevM-xr11OEQuOJChg0hYjZXthtYoGWCGw3IAfI2ldcEoPDPegwrG9vjDhAabfmHbBfwd_ihtSOlUc4m7sY1D3DrAIF27xPA5gDPQKzhEO1q2Ho429QC93N48T--Tx6e7h-nVY6JYKkKi85nIoCijWUk4k5QrXuR1rqEo6pIKXWtGNc0kpDXPaVrWNU3rMv6PEJoJyQ7Q6Vp3cDZa9qHqjFfQtrIHO_qKFjlnVEQ2omdrVDnrvQNdDc500i0rSqqfSKrfSKp1JBE_2SiPdQezf_gvA_YNo6-NGA</recordid><startdate>201501</startdate><enddate>201501</enddate><creator>Weiss, Gabriel</creator><creator>Tsagakis, Konstantinos</creator><creator>Jakob, Heinz</creator><creator>Di Bartolomeo, Roberto</creator><creator>Pacini, Davide</creator><creator>Barberio, Giuseppe</creator><creator>Mascaro, Jorge</creator><creator>Mestres, Carlos-A</creator><creator>Sioris, Thanos</creator><creator>Grabenwoger, Martin</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201501</creationdate><title>The frozen elephant trunk technique for the treatment of complicated type B aortic dissection with involvement of the aortic arch: multicentre early experience</title><author>Weiss, Gabriel ; Tsagakis, Konstantinos ; Jakob, Heinz ; Di Bartolomeo, Roberto ; Pacini, Davide ; Barberio, Giuseppe ; Mascaro, Jorge ; Mestres, Carlos-A ; Sioris, Thanos ; Grabenwoger, Martin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c329t-f5d94e68794a073a17c765b5fe66b819fbf31f14ae2b75128bb12b809300149a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aneurysm, Dissecting - epidemiology</topic><topic>Aneurysm, Dissecting - mortality</topic><topic>Aneurysm, Dissecting - surgery</topic><topic>Aorta, Thoracic - surgery</topic><topic>Aortic Aneurysm, Thoracic - epidemiology</topic><topic>Aortic Aneurysm, Thoracic - mortality</topic><topic>Aortic Aneurysm, Thoracic - surgery</topic><topic>Blood Vessel Prosthesis Implantation - adverse effects</topic><topic>Blood Vessel Prosthesis Implantation - methods</topic><topic>Female</topic><topic>Humans</topic><topic>Kaplan-Meier Estimate</topic><topic>Male</topic><topic>Middle Aged</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Weiss, Gabriel</creatorcontrib><creatorcontrib>Tsagakis, Konstantinos</creatorcontrib><creatorcontrib>Jakob, Heinz</creatorcontrib><creatorcontrib>Di Bartolomeo, Roberto</creatorcontrib><creatorcontrib>Pacini, Davide</creatorcontrib><creatorcontrib>Barberio, Giuseppe</creatorcontrib><creatorcontrib>Mascaro, Jorge</creatorcontrib><creatorcontrib>Mestres, Carlos-A</creatorcontrib><creatorcontrib>Sioris, Thanos</creatorcontrib><creatorcontrib>Grabenwoger, Martin</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of cardio-thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Weiss, Gabriel</au><au>Tsagakis, Konstantinos</au><au>Jakob, Heinz</au><au>Di Bartolomeo, Roberto</au><au>Pacini, Davide</au><au>Barberio, Giuseppe</au><au>Mascaro, Jorge</au><au>Mestres, Carlos-A</au><au>Sioris, Thanos</au><au>Grabenwoger, Martin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The frozen elephant trunk technique for the treatment of complicated type B aortic dissection with involvement of the aortic arch: multicentre early experience</atitle><jtitle>European journal of cardio-thoracic surgery</jtitle><addtitle>Eur J Cardiothorac Surg</addtitle><date>2015-01</date><risdate>2015</risdate><volume>47</volume><issue>1</issue><spage>106</spage><epage>114</epage><pages>106-114</pages><issn>1010-7940</issn><eissn>1873-734X</eissn><abstract>Providing effective treatment for complicated type B aortic dissection (AD) with concomitant pathologies of the aortic arch or ascending aorta is challenging, especially if the aortic anatomy is contraindicated for thoracic endovascular aortic repair (TEVAR). We present the early results of a multicentre study using the frozen elephant trunk (FET) technique for type B AD.
From January 2005 to March 2013, data from 465 patients who had undergone treatment with the FET technique were collected in the database of the International E-vita Open Registry. From this cohort, 57 patients who had a primary indication for surgery for type B AD were included in the present study. Their mean age was 58±12 years, and 72% had a chronic dissection. All operations were performed in circulatory arrest and bilateral antegrade cerebral perfusion. Computed aortic imaging was performed for false lumen (FL) evaluation during the follow-up.
The in-hospital mortality rate was 14% (8/57). Stroke and spinal cord injury occurred in 6 (10%) and 2 patients (4%), respectively. The rate of immediate FL thrombosis at the level of the stent graft was 75% (40/53) and increased to 97% (41/42) during the follow-up period (23±19 months). Distally, at the level of the abdominal aorta, the FL remained patent in 50% (21/42) of patients. The 1- and 3-year survival was 81 and 75%, respectively.
The FET technique is a feasible therapeutic option for complicated type B AD with involvement of the aortic arch if TEVAR is contraindicated. In contrast to conventional aortic surgery via a lateral thoracotomy, the FET procedure can provide simultaneous treatment of the ascending aorta and aortic arch.</abstract><cop>Germany</cop><pmid>24599159</pmid><doi>10.1093/ejcts/ezu067</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Aged Aneurysm, Dissecting - epidemiology Aneurysm, Dissecting - mortality Aneurysm, Dissecting - surgery Aorta, Thoracic - surgery Aortic Aneurysm, Thoracic - epidemiology Aortic Aneurysm, Thoracic - mortality Aortic Aneurysm, Thoracic - surgery Blood Vessel Prosthesis Implantation - adverse effects Blood Vessel Prosthesis Implantation - methods Female Humans Kaplan-Meier Estimate Male Middle Aged |
title | The frozen elephant trunk technique for the treatment of complicated type B aortic dissection with involvement of the aortic arch: multicentre early experience |
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