Saikosaponin b2 is a naturally occurring terpenoid that efficiently inhibits hepatitis C virus entry

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Veröffentlicht in:	Journal of hepatology 2015-03, Vol.62 (3), p.541-548
Hauptverfasser:	Lin, Liang-Tzung, Chung, Chueh-Yao, Hsu, Wen-Chan, Chang, Shun-Pang, Hung, Ting-Chun, Shields, Justin, Russell, Rodney S, Lin, Chih-Chan, Li, Chien-Feng, Yen, Ming-Hong, Tyrrell, D. Lorne J, Lin, Chun-Ching, Richardson, Christopher D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiviral Antiviral Agents - isolation & purification Antiviral Agents - pharmacology Antiviral Agents - toxicity Bupleurum Cell Line Gastroenterology and Hepatology Hepacivirus - drug effects Hepacivirus - physiology Hepatitis C - prevention & control Hepatitis C virus Hepatocytes - drug effects Hepatocytes - virology Humans Inhibitor Liver transplant Liver Transplantation Male Oleanolic Acid - analogs & derivatives Oleanolic Acid - isolation & purification Oleanolic Acid - pharmacology Oleanolic Acid - toxicity Plant Extracts - isolation & purification Plant Extracts - pharmacology Rats Rats, Sprague-Dawley Saikosaponin Saponins - isolation & purification Saponins - pharmacology Saponins - toxicity Virion - drug effects Virus entry Virus Internalization - drug effects Virus Replication - drug effects
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