Methylene blue for burn-induced vasoplegia: case report and review of literature
We report the use of a single dose of methylene blue in a patient with burn-induced vasoplegia refractory to fluids, vasopressors, and steroids. Administration of methylene blue allowed for cessation of epinephrine infusion within 2 hours of administration, and reduction in excessive fluid resuscita...
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| Veröffentlicht in: | Journal of burn care & research 2015-03, Vol.36 (2), p.e107-e111 |
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| container_issue | 2 |
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| container_title | Journal of burn care & research |
| container_volume | 36 |
| creator | Church, Joseph T Posluszny, Joseph A Hemmila, Mark To, Kathleen B Cherry-Bukowiec, Jill R Waljee, Jennifer |
| description | We report the use of a single dose of methylene blue in a patient with burn-induced vasoplegia refractory to fluids, vasopressors, and steroids. Administration of methylene blue allowed for cessation of epinephrine infusion within 2 hours of administration, and reduction in excessive fluid resuscitation. The patient's clinical course continued for 2 months and was complicated by severe acute respiratory distress syndrome, pneumonia, septic shock, poor skin graft adherence, renal failure requiring continuous renal replacement therapy, cutaneous mucormycosis, and ultimately, withdrawal of care and death. Despite the eventual outcome, this is the longest reported survival following methylene blue administration for vasoplegia secondary to burn injury. |
| doi_str_mv | 10.1097/BCR.0000000000000134 |
| format | Article |
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| ispartof | Journal of burn care & research, 2015-03, Vol.36 (2), p.e107-e111 |
| issn | 1559-047X 1559-0488 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Complete; Oxford University Press Journals All Titles (1996-Current) |
| subjects | Burns - complications Burns - drug therapy Enzyme Inhibitors - therapeutic use Evidence-Based Medicine Humans Male Methylene Blue - therapeutic use Middle Aged Treatment Failure Vasoplegia - drug therapy Vasoplegia - etiology |
| title | Methylene blue for burn-induced vasoplegia: case report and review of literature |
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