Synthesis of 2,3-Dideoxy-2-fluoro-2,3-endo-methylene- and 2,3-Dideoxy-2-fluoro-3‑C‑hydroxymethyl-2,3-endo-methylene-pentofuranoses and Their Use in the Preparation of Conformationally Locked Bicyclic Nucleosides

Construction of protected 2,3-dideoxy-2-fluoro-2,3-endo-methylene-pento­furanoses from d-glyceraldehyde and 2,3-dideoxy-2-fluoro-3-C-hydroxy­methyl-2,3-endo-methylene-pento­furanoses from d-isoascorbic acid, via Simmons–Smith-type stereoselective cyclopropanations on the respective fluoroallyl alcoh...

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Veröffentlicht in:Journal of organic chemistry 2015-02, Vol.80 (4), p.2198-2215
Hauptverfasser: Clarkson, Rob, Komsta, Zofia, Mayes, Benjamin A, Moussa, Adel, Shelbourne, Montserrat, Stewart, Alistair, Tyrrell, Andrew J, Wallis, Laura L, Weymouth-Wilson, Alexander C
Format: Artikel
Sprache:eng
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