A novel repressor of P element transposition in Drosophila melanogaster
We have discovered, in an inbred line (Loua) of Drosophila melanogaster from Zaïre, a third chromosome showing unusual P element repression. Repression of P element transposition by this chromosome, named Loua3, is dominant zygotic and has three unusual properties. Firstly, its repression of the gon...
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| Veröffentlicht in: | Genetical Research 1998-02, Vol.71 (1), p.21-30 |
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| creator | BADGE, RICHARD M. BROOKFIELD, JOHN F. Y. |
| description | We have discovered, in an inbred line (Loua) of
Drosophila melanogaster from Zaïre, a third
chromosome showing unusual P element repression. Repression of P element
transposition by this
chromosome, named Loua3, is dominant zygotic and has three
unusual properties. Firstly, its
repression of the gonadal dysgenesis caused by a strong P haplotype is
strongly
temperature-dependent, being most evident at higher rearing temperatures.
Secondly, subdivision of Loua3 by
recombination abolishes repression: the effect is apparently a function
of
the intact chromosome.
Finally, Loua3 also diminishes somatic lethality when chromosomes
carrying many ‘ammunition’
elements (Birmingham2) are exposed to the constitutive transposase source
Δ2-3(99B). The
chromosome has 17 P elements, none full-length, located in at least 12
dispersed positions. |
| doi_str_mv | 10.1017/S0016672397003066 |
| format | Article |
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Drosophila melanogaster from Zaïre, a third
chromosome showing unusual P element repression. Repression of P element
transposition by this
chromosome, named Loua3, is dominant zygotic and has three
unusual properties. Firstly, its
repression of the gonadal dysgenesis caused by a strong P haplotype is
strongly
temperature-dependent, being most evident at higher rearing temperatures.
Secondly, subdivision of Loua3 by
recombination abolishes repression: the effect is apparently a function
of
the intact chromosome.
Finally, Loua3 also diminishes somatic lethality when chromosomes
carrying many ‘ammunition’
elements (Birmingham2) are exposed to the constitutive transposase source
Δ2-3(99B). The
chromosome has 17 P elements, none full-length, located in at least 12
dispersed positions.</description><identifier>ISSN: 0016-6723</identifier><identifier>EISSN: 1469-5073</identifier><identifier>DOI: 10.1017/S0016672397003066</identifier><identifier>PMID: 9674380</identifier><language>eng</language><publisher>England: Cambridge University Press</publisher><subject>Animals ; DNA Transposable Elements ; Drosophila melanogaster ; Drosophila melanogaster - genetics ; Female ; Haplotypes ; Hot Temperature ; Male</subject><ispartof>Genetical Research, 1998-02, Vol.71 (1), p.21-30</ispartof><rights>1998 Cambridge University Press</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c421t-aac55194a3e8e563215a04545aaa506fc61531c7d26fd097972cb727ca9d73f13</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.cambridge.org/core/product/identifier/S0016672397003066/type/journal_article$$EHTML$$P50$$Gcambridge$$H</linktohtml><link.rule.ids>314,780,784,23318,27924,27925,55804</link.rule.ids><linktorsrc>$$Uhttps://www.cambridge.org/core/product/identifier/S0016672397003066/type/journal_article$$EView_record_in_Cambridge_University_Press$$FView_record_in_$$GCambridge_University_Press</linktorsrc><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9674380$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>BADGE, RICHARD M.</creatorcontrib><creatorcontrib>BROOKFIELD, JOHN F. Y.</creatorcontrib><title>A novel repressor of P element transposition in Drosophila melanogaster</title><title>Genetical Research</title><addtitle>Genet. Res</addtitle><description>We have discovered, in an inbred line (Loua) of
Drosophila melanogaster from Zaïre, a third
chromosome showing unusual P element repression. Repression of P element
transposition by this
chromosome, named Loua3, is dominant zygotic and has three
unusual properties. Firstly, its
repression of the gonadal dysgenesis caused by a strong P haplotype is
strongly
temperature-dependent, being most evident at higher rearing temperatures.
Secondly, subdivision of Loua3 by
recombination abolishes repression: the effect is apparently a function
of
the intact chromosome.
Finally, Loua3 also diminishes somatic lethality when chromosomes
carrying many ‘ammunition’
elements (Birmingham2) are exposed to the constitutive transposase source
Δ2-3(99B). The
chromosome has 17 P elements, none full-length, located in at least 12
dispersed positions.</description><subject>Animals</subject><subject>DNA Transposable Elements</subject><subject>Drosophila melanogaster</subject><subject>Drosophila melanogaster - genetics</subject><subject>Female</subject><subject>Haplotypes</subject><subject>Hot Temperature</subject><subject>Male</subject><issn>0016-6723</issn><issn>1469-5073</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kF9LwzAUxYMoc04_gA9CnnyrJk2TtI9D3VQG_kfwJWTp7exsm5q0ot_ejI29CD5dLr9zLucehI4pOaOEyvMnQqgQMmaZJIQRIXbQkCYiiziRbBcNVzha8X104P0yrIykcoAGmZAJS8kQTce4sV9QYQetA--tw7bA9xgqqKHpcOd041vry660DS4bfOmst-17WWlcQ6Ubu9C-A3eI9gpdeTjazBF6mVw9X1xHs7vpzcV4Fpkkpl2kteGcZolmkAIXLKZck4QnXGvNiSiMoJxRI_NYFDnJZCZjM5exNDrLJSsoG6HT9d3W2c8efKfq0huoQhKwvVdUcC7jLA1CuhaaENg7KFTrylq7H0WJWpWn_pQXPCeb4_28hnzr2LQVeLTmZXj5e4u1-1BCMsmVmD6oN85Eejt5VY9BzzYZdD13Zb4AtbS9a0JB_6T4BWPOh44</recordid><startdate>199802</startdate><enddate>199802</enddate><creator>BADGE, RICHARD M.</creator><creator>BROOKFIELD, JOHN F. Y.</creator><general>Cambridge University Press</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SS</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope><scope>RC3</scope></search><sort><creationdate>199802</creationdate><title>A novel repressor of P element transposition in Drosophila melanogaster</title><author>BADGE, RICHARD M. ; BROOKFIELD, JOHN F. Y.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c421t-aac55194a3e8e563215a04545aaa506fc61531c7d26fd097972cb727ca9d73f13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Animals</topic><topic>DNA Transposable Elements</topic><topic>Drosophila melanogaster</topic><topic>Drosophila melanogaster - genetics</topic><topic>Female</topic><topic>Haplotypes</topic><topic>Hot Temperature</topic><topic>Male</topic><toplevel>online_resources</toplevel><creatorcontrib>BADGE, RICHARD M.</creatorcontrib><creatorcontrib>BROOKFIELD, JOHN F. Y.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><jtitle>Genetical Research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BADGE, RICHARD M.</au><au>BROOKFIELD, JOHN F. Y.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A novel repressor of P element transposition in Drosophila melanogaster</atitle><jtitle>Genetical Research</jtitle><addtitle>Genet. Res</addtitle><date>1998-02</date><risdate>1998</risdate><volume>71</volume><issue>1</issue><spage>21</spage><epage>30</epage><pages>21-30</pages><issn>0016-6723</issn><eissn>1469-5073</eissn><abstract>We have discovered, in an inbred line (Loua) of
Drosophila melanogaster from Zaïre, a third
chromosome showing unusual P element repression. Repression of P element
transposition by this
chromosome, named Loua3, is dominant zygotic and has three
unusual properties. Firstly, its
repression of the gonadal dysgenesis caused by a strong P haplotype is
strongly
temperature-dependent, being most evident at higher rearing temperatures.
Secondly, subdivision of Loua3 by
recombination abolishes repression: the effect is apparently a function
of
the intact chromosome.
Finally, Loua3 also diminishes somatic lethality when chromosomes
carrying many ‘ammunition’
elements (Birmingham2) are exposed to the constitutive transposase source
Δ2-3(99B). The
chromosome has 17 P elements, none full-length, located in at least 12
dispersed positions.</abstract><cop>England</cop><pub>Cambridge University Press</pub><pmid>9674380</pmid><doi>10.1017/S0016672397003066</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0016-6723 |
| ispartof | Genetical Research, 1998-02, Vol.71 (1), p.21-30 |
| issn | 0016-6723 1469-5073 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_16557298 |
| source | Cambridge Journals Open Access |
| subjects | Animals DNA Transposable Elements Drosophila melanogaster Drosophila melanogaster - genetics Female Haplotypes Hot Temperature Male |
| title | A novel repressor of P element transposition in Drosophila melanogaster |
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