A retrospective study to evaluate single agent methotrexate treatment in low risk gestational choriocarcinoma in the United Kingdom

Abstract Objective To determine whether single agent chemotherapy with intramuscular methotrexate 50 mg administered on days 1, 3, 5, and 7 and oral folinic acid 15 mg administered on days 2, 4, 6, and 8 in 2 weekly cycles (IM MTX/FA) is an effective treatment regimen for patients with low risk gest...

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Veröffentlicht in:	Gynecologic oncology 2015-02, Vol.136 (2), p.258-263
Hauptverfasser:	Taylor, F, Short, D, Winter, M.C, Tidy, J, Savage, P.M, Sarwar, N, Hancock, B.W, Seckl, M.J, Coleman, R.E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antimetabolites, Antineoplastic - therapeutic use Chemotherapy Choriocarcinoma - blood Choriocarcinoma - drug therapy Chorionic Gonadotropin - blood Female FIGO/WHO prognostic staging system Gestational choriocarcinoma Gestational Trophoblastic Disease - blood Gestational Trophoblastic Disease - drug therapy Hematology, Oncology and Palliative Medicine Humans Low risk Methotrexate Methotrexate - therapeutic use Obstetrics and Gynecology Pregnancy Resistance Retrospective Studies Risk Factors United Kingdom
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