Changes in proton currents in murine microglia induced by cytoskeletal disruptive agents

Voltage-gated proton currents (I PR) were investigated in cultured murine microglia using the whole-cell configuration of the patch clamp technique. At a gradient of 1.5 between intracellular (pH i=6.0) and extracellular pH (pH o=7.5) values, outward I PR were detected at depolarizing potentials, wh...

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Veröffentlicht in:	Neuroscience letters 1998-05, Vol.247 (2), p.191-194
Hauptverfasser:	Klee, Rolf, Heinemann, Uwe, Eder, Claudia
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials Animals Biological and medical sciences Brain macrophages Cells, Cultured Colchicine Colchicine - pharmacology Cytochalasin D Cytochalasin D - pharmacology Cytoskeleton - drug effects Cytoskeleton - physiology Fundamental and applied biological sciences. Psychology H + currents Ion Transport - drug effects Isolated neuron and nerve. Neuroglia Mice Microglia - drug effects Microglia - metabolism Microtubules - drug effects Microtubules - physiology Paclitaxel - pharmacology Patch-Clamp Techniques Phalloidin Phalloidine - pharmacology Protons Taxol Vertebrates: nervous system and sense organs
Online-Zugang:	Volltext
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